Structural Characterization and Quantitation of Ether-Linked Glycerophospholipids in Peroxisome Biogenesis Disorder Tissue by Ultraviolet Photodissociation Mass Spectrometry

Autor: Molly S. Blevins, Samuel W. J. Shields, Wei Cui, Wedad Fallatah, Ann B. Moser, Nancy E. Braverman, Jennifer S. Brodbelt
Rok vydání: 2022
Předmět:
Zdroj: Analytical Chemistry. 94:12621-12629
ISSN: 1520-6882
0003-2700
Popis: The biological impact of ether glycerophospholipids (GP) in peroxisomal disorders and other diseases makes them significant targets as biomarkers for diagnostic assays or deciphering pathology of the disorders. Ether lipids include both plasmanyl and plasmenyl lipids, which each contain an ether or a vinyl ether bond at the
Databáze: OpenAIRE