Supplementary Figures from Identification of Lethal microRNAs Specific for Head and Neck Cancer

Autor: Ruud H. Brakenhoff, Boudewijn J.M. Braakhuis, C. René Leemans, Francesco Cerisoli, Reuven Agami, Bauke Ylstra, Wessel N. van Wieringen, Michiel de Maaker, Sanne R. Martens-de Kemp, Marlon Lindenbergh-van der Plas
Rok vydání: 2023
DOI: 10.1158/1078-0432.22450331.v1
Popis: PDF file, 96K, Supplementary Figure S1 First validation of the identified 19 microRNAs that seemed to elicit a tumor-selective lethal effect. Supplementary Figure S2 Effect of the six tumor-selective microRNAs on non-HNSCC cell lines. Supplementary Figure S3 Phenotypic effect of miR-181a overexpression in time, either when introduced by retroviral transduction or transient transfection in HNSCC cell line VU-SCC-120. Supplementary Figure S4 ATM expression after transient transfection of expression constructs with ATM and a kinase-dead ATM mutant lacking the 3'UTR of ATM.
Databáze: OpenAIRE