Studies on human N-acetyl-β-d -hexosaminidase C separated from neonatal brain
| Autor: | D M Broadhead, G T N Besley |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Size-exclusion chromatography
Biochemistry Isozyme Pregnancy N-Acetyl-beta-D-hexosaminidase Pi medicine Neonatal brain Humans Fetal Death Molecular Biology chemistry.chemical_classification Chemistry Infant Newborn Brain Cell Biology Human brain Isoenzymes Kinetics Hexosaminidases Enzyme medicine.anatomical_structure Sephadex Chromatography Gel Female Isoelectric Focusing Hymecromone Research Article |
| Zdroj: | Biochemical Journal. 155:205-208 |
| ISSN: | 0264-6021 |
| Popis: | Human brain hexosaminidase C was separated from isoenzymes A and B by Sephadex G-200 gel filtration. Properties of the enzyme were studied, particularly its isoelectric-focusing profile, pI4.80. These findings indicate that hexosaminidase C is identical with the major residual component of Sandhoff fibroblasts with respect to substrate specificity, pI and activity pH optimum. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|