Scorpion sting nephropathy
| Autor: | Chaitanya Prabhu, Stalin Viswanathan |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
kidney
renal failure Pathology medicine.medical_specialty Interstitial nephritis venom Venom complex mixtures Nephropathy medicine scorpion envenomation Envenomation Acute tubular necrosis Transplantation Kidney business.industry I. Special Features in-Depth Clinical Reviews medicine.disease Sting medicine.anatomical_structure scorpion sting Nephrology Immunology Hemoglobinuria business |
| Zdroj: | NDT Plus |
| ISSN: | 2048-8513 2048-8505 |
| DOI: | 10.1093/ndtplus/sfr148 |
| Popis: | Scorpion envenomations are ubiquitous, but nephropathy is a rare manifestation, reported mainly from the Middle East and North Africa. Rapid venom redistribution from blood, delayed excretion from the kidneys, direct toxicity of venom enzymes, cytokine release and afferent arteriolar constriction have been seen in experimental animals. Haemoglobinuria, acute tubular necrosis, interstitial nephritis and haemolytic-uraemic syndrome have been documented in human victims of scorpion envenomation. Epidemiology, venom components and toxins, effects on the laboratory mammals especially the kidneys and reports of renal failure in humans are reviewed in this article. |
| Databáze: | OpenAIRE |
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