Use of ambulatory blood pressure monitoring data to predict left ventricular mass in hypertension
| Autor: | Jean-Philippe Baguet, Antoniadis A, J. P. Siche, de Gaudemaris R, J. M. Mallion, F. Tremel |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Male medicine.medical_specialty Ambulatory blood pressure Multivariate analysis Blood Pressure Assessment and Diagnosis Left ventricular mass Electrocardiography Heart Rate Predictive Value of Tests Internal medicine Heart rate Internal Medicine medicine Humans Advanced and Specialized Nursing business.industry General Medicine Blood Pressure Monitoring Ambulatory Middle Aged Blood pressure Hypertension Cardiology Linear Models Female Hypertrophy Left Ventricular Cardiology and Cardiovascular Medicine business |
| Zdroj: | Blood pressure monitoring. 6(2) |
| ISSN: | 1359-5237 |
| Popis: | BACKGROUND Many studies have shown definite but weak correlations between 24h blood pressure and left ventricular mass in hypertension. OBJECTIVE The present study applied an original multivariate analysis of parameters from ambulatory blood pressure monitoring to predict left ventricular mass in hypertension. METHODS Two hundred untreated hypertensive subjects (age=51+/-13 years, clinic blood pressure=163/98mmHg) had echocardiography and 24h recording of blood pressure. Data from 102 subjects were used to construct a mathematical model for prediction of left ventricular mass. The remaining 98 subjects were used to validate the model. RESULTS The model included age, weight, height, 24h systolic blood pressure, heart rate over 24h, standard deviations of systolic blood pressure and of heart rate over 24h. Using this model, we explained 63% of the variance of left ventricular mass. Moreover, the model was validated for the correlation (r=0.70) between measured and the estimated left ventricular mass. CONCLUSIONS Systolic blood pressure, heart rate and their standard deviations over 24h contribute to left ventricular mass in hypertensive subjects. Thus, it is important to take into account not only blood pressure but also heart rate in clinical studies. |
| Databáze: | OpenAIRE |
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