A brain centred view of psychiatric comorbidity in tinnitus: from otology to hodology
| Autor: | Francesco Saverio Bersani, Amedeo Minichino, Filippo Mazzei, Roberta Panico, Giancarlo Altissimi, Valeria Testugini, Graziella Francesca Romano, Giuseppe Valeriani, Massimo Salviati, Giancarlo Cianfrone |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
psychiatric comorbidity
tinnitus neuroplastic phenomena Prefrontal Cortex Review Article Electroencephalography Auditory cortex lcsh:RC321-571 Neuroplasticity medicine otorhinolaryngologic diseases Arcuate fasciculus Animals Humans Prefrontal cortex lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Auditory Cortex medicine.diagnostic_test Mental Disorders Brain Magnetoencephalography Magnetic Resonance Imaging Dorsolateral prefrontal cortex medicine.anatomical_structure Diffusion Tensor Imaging Neurology Positron-Emission Tomography Neurology (clinical) medicine.symptom Psychology Insula Neuroscience Tinnitus |
| Zdroj: | Neural Plasticity Neural Plasticity, Vol 2014 (2014) |
| Popis: | Introduction. Comorbid psychiatric disorders are frequent among patients affected by tinnitus. There are mutual clinical influences between tinnitus and psychiatric disorders, as well as neurobiological relations based on partially overlapping hodological and neuroplastic phenomena. The aim of the present paper is to review the evidence of alterations in brain networks underlying tinnitus physiopathology and to discuss them in light of the current knowledge of the neurobiology of psychiatric disorders.Methods. Relevant literature was identified through a search on Medline and PubMed; search terms included tinnitus, brain, plasticity, cortex, network, and pathways.Results. Tinnitus phenomenon results from systemic-neurootological triggers followed by neuronal remapping within several auditory and nonauditory pathways. Plastic reorganization and white matter alterations within limbic system, arcuate fasciculus, insula, salience network, dorsolateral prefrontal cortex, auditory pathways, ffrontocortical, and thalamocortical networks are discussed.Discussion. Several overlapping brain network alterations do exist between tinnitus and psychiatric disorders. Tinnitus, initially related to a clinicoanatomical approach based on a cortical localizationism, could be better explained by an holistic or associationist approach considering psychic functions and tinnitus as emergent properties of partially overlapping large-scale neural networks. |
| Databáze: | OpenAIRE |
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