Mediterranean diet and depression: a population-based cohort study
Autor: | Ruoqing Chen, Weiyao Yin, Sven Sandin, Fang Fang, Christina M. Hultman, Marie Löf |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Depression
Mental health Mediterranean Diet womens health Cohort studies Epidemiology medicine.medical_specialty RC620-627 Mediterranean diet Medicine (miscellaneous) Physical Therapy Sports Therapy and Rehabilitation Diet Mediterranean Lower risk Risk Factors women’s health medicine Humans Nutritional diseases. Deficiency diseases Depression (differential diagnoses) Proportional Hazards Models Nutrition and Dietetics business.industry Research Hazard ratio Public Health Global Health Social Medicine and Epidemiology Middle Aged Confidence interval Middle age Folkhälsovetenskap global hälsa socialmedicin och epidemiologi Female Public aspects of medicine RA1-1270 business Demography Cohort study |
Zdroj: | International Journal of Behavioral Nutrition and Physical Activity, Vol 18, Iss 1, Pp 1-10 (2021) The International Journal of Behavioral Nutrition and Physical Activity |
ISSN: | 1479-5868 |
Popis: | Background Depression imposes immense public health burden, demonstrating an urgent need of the identification of modifiable risk factors. Only a few cohort studies have analyzed the association between Mediterranean dietary pattern (MDP) and depression but with mixed results. We examined the impact of MDP on clinically ascertained depression in a large population-based dataset. Methods In 1991/92, detailed information on diet, using a food frequency questionnaire, and potential confounding factors (body weight, height, educational attainment, smoking, previous diabetes and hypertension, and physical activity) was collected, in a random sample of 49,261 Swedish women aged 29-49. Adherence to MDP was calculated. Clinical depression was extracted from the National Patient Register. Study participants were followed up through 2012. Results During an average follow-up of 20.4 years, 1677 incident cases of depression were diagnosed. We observed a lower risk of depression for medium (score 4-5) and high (6-9) adherence to MDP, compared with low (0-3) adherence (Medium: hazard ratio (HR) = 0.90, 95% confidence interval (CI) = 0.81-1.00; High: HR = 0.82, 95%CI = 0.71-0.94). Per unit increase of adherence, the risk of depression was reduced by 5% (HR = 0.95, 95%CI = 0.92-0.98). The association became stronger when restricting to severe form of depression (HR = 0.51, 95%CI = 0.33-0.76). The HRs were higher from age 50 onward both over the first and the second 10-year follow-up period, compared with before age 50, indicating stronger association with increasing age. Results remained after extensive sensitivity analyses. Conclusion Higher adherence to a Mediterranean diet at middle age was associated with a lower risk of depression later in life among Swedish women. |
Databáze: | OpenAIRE |
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