Treatment and follow‐up of persistent granulomatous cheilitis with intralesional steroid and metronidazole
| Autor: | Yunus Saral, Demet Cicek, Nusret Akpolat, Başak Kandi Coşkun |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
medicine.medical_specialty
Erythema medicine.drug_class Dermatology Injections Intralesional Recurrence Metronidazole Melkersson–Rosenthal syndrome Edema medicine Humans Glucocorticoids Melkersson-Rosenthal Syndrome business.industry Middle Aged medicine.disease Lip Facial paralysis Surgery Etiology Corticosteroid Drug Therapy Combination Female medicine.symptom business medicine.drug Rare disease |
| Zdroj: | Journal of Dermatological Treatment. 15:333-335 |
| ISSN: | 1471-1753 0954-6634 |
| DOI: | 10.1080/09546630410015538 |
| Popis: | Granulomatous cheilitis (GC) is a chronic edema which frequently affects the upper lip due to granulomatous inflammation. Its etiology is currently unknown. This rare disease is generally accompanied by Melkersson-Rosenthal syndrome (MRS), characterized by scrotal tongue, orofacial edema and facial paralysis. However, it is also known to develop only with orofacial edema. Granulomatous cheilitis is a difficult disease to treat because of recurrences. There are contradictory reports about the results of treatment without surgical intervention and the rates of recurrence. Our case was a 57-year-old female patient who was characterized by orofacial edema only. The edema and erythema had persisted for 1 year before admission. In the present case, application of intralesional corticosteroid treatment as a total of three injections over 3 consecutive months (one injection per month) and the accompanying metronidazole treatment brought about successful results. No recurrence was observed in the follow-up. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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