A Mediterranean Diet with an Enhanced Consumption of Extra Virgin Olive Oil and Pistachios Improves Pregnancy Outcomes in Women Without Gestational Diabetes Mellitus: A Sub-Analysis of the St. Carlos Gestational Diabetes Mellitus Prevention Study
| Autor: | Alfonso L. Calle-Pascual, María José Torrejón, Inés Jiménez, Carmen Montañez, Isabelle Runkle, Elena Bordiú, Alejandra Durán, Isabel Ortega, García de la Torre N, Francisco J. Illana, Ana Barabash, Cristina Familiar, Carla Assaf-Balut, Nuria Izquierdo, de Miguel P, Miguel Herraiz, Miguel A. Rubio, Maria Angeles Cuadrado, Johanna Valerio, Manuel Fuentes, Inmaculada Moraga, Del Valle L, Martin Cuesta |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
0301 basic medicine medicine.medical_specialty Mediterranean diet Extra-virgin olive oil Medicine (miscellaneous) 030209 endocrinology & metabolism Diet Mediterranean Fetal Macrosomia Preeclampsia 03 medical and health sciences 0302 clinical medicine Pregnancy Diabetes mellitus medicine Humans Nuts Prospective Studies Olive Oil Original Paper Pregnancy outcomes 030109 nutrition & dietetics Nutrition and Dietetics Cesarean Section business.industry Obstetrics Infant Newborn Pregnancy Outcome food and beverages Gestational age medicine.disease Gestational diabetes Diabetes Gestational Relative risk Infant Small for Gestational Age Pistacia Urinary Tract Infections Small for gestational age Female business |
| Zdroj: | Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid Consejería de Sanidad de la Comunidad de Madrid |
| ISSN: | 1421-9697 0250-6807 |
| DOI: | 10.1159/000495793 |
| Popis: | Aims: The aim of the study was to evaluate the effect of a Mediterranean diet (MedDiet), enhanced with extra virgin olive oil (EVOO) and nuts, on a composite of adverse maternofoetal outcomes of women with normoglycemia during pregnancy. Methods: This was a sub-analysis of the St Carlos gestational diabetes mellitus Prevention Study. Only normoglycemic women were analysed (697). They were randomized (at 8–12th gestational weeks) to: standard-care control group (337), where fat consumption was limited to 30% of total caloric intake; or intervention group (360), where a MedDiet, enhanced with EVOO and pistachios (40–42% fats of total caloric intake) was recommended. The primary outcome was a composite of maternofoetal outcomes (CMFOs): at least having 1 event of emergency C-section, perineal trauma, pregnancy-induced hypertension and preeclampsia, prematurity, large-for-gestational-age and small-for gestational-age. Results: Crude relative risk showed that the intervention was associated with a significant reduction in the risk of CMFOs (0.48 [0.37–0.63]; p = 0.0001), with a number-needed-to-treat = 5. Risk of urinary tract infections, emergency C-sections, perineal trauma, large-for-gestational-age and small-for gestational age new-borns were also significantly reduced. Conclusion: A MedDiet, enhanced with EVOO and nuts, was associated with a risk reduction of CMFOs in over 50% in normoglycemic pregnant women. Therefore, it might be a potentially adequate diet for pregnant women. Trial registration: Identifier ISRCTN84389045. The study was registered on September 27, 2013. Last edited on September 26, 2018 |
| Databáze: | OpenAIRE |
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