Assessment of periodontitis and its role in viridans streptococcal bacteremia and infective endocarditis
| Autor: | Basavraj Nagoba, Shree Dhotre, Ramesh Patil, Vilas Jahagirdar, Milind Davane, Namdev M Suryawanshi |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty RD1-811 Gingiva Bacteremia 030204 cardiovascular system & hematology Gastroenterology Group B 03 medical and health sciences 0302 clinical medicine Risk Factors Streptococcal Infections Internal medicine medicine Humans Diseases of the circulatory (Cardiovascular) system Streptococcal bacteremia Periodontitis biology Potential risk business.industry Significant difference Viridans group streptococci Endocarditis Bacterial 030206 dentistry Middle Aged Viridans Streptococci medicine.disease biology.organism_classification Viridans streptococci RC666-701 Infective endocarditis Female Surgery Clinical and Preventive Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Indian Heart Journal, Vol 70, Iss 2, Pp 225-232 (2018) Indian Heart Journal |
| ISSN: | 0019-4832 |
| DOI: | 10.1016/j.ihj.2017.06.019 |
| Popis: | Objectives: To evaluate the role of periodontitis in viridans group streptococci (VGS) bacteremia and infective endocarditis (IE). Methods: A total of 200 subjects including two groups. Group A- 34 subjects undergoing tooth extraction with periodontitis, 46 subjects undergoing tooth extraction without periodontitis and 40 healthy controls. Group B: 40 confirmed cases of IE (17 with and 23 without periodontitis) and 40 healthy controls. Subgingival plaque and blood samples were obtained and processed by standard procedures. Results: A total of 53 blood samples (66.25%) yielded positive cultures after tooth extraction. The relationship between the presence of periodontitis and a positive blood culture was significantly higher (p = 0.05) for tooth extraction cases with periodontitis (79.40%) than tooth extraction cases without periodontitis (56.50%). Periodontitis was observed in 42.5% of IE cases. Out of the 40 patients of IE, the blood samples yielded 40 different isolates, majority were viridans streptococci 15 (37.5%) and staphylococci nine (22.5%). No statistically significant difference was observed between the subgingival plaque and blood isolates of periodontitis in both the groups, indicating similarity of biotypes of viridans streptococci isolated from the blood and the subgingival plaque. Similarity was also observed between the antibiogram profiles of viridans streptococci from both the groups. Conclusions: Periodontitis enhances viridans streptococcal bacteremia and may be a potential risk factor for IE. Keywords: Infective endocarditis, Periodontitis, Viridans group streptococci |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|