A comparison between measured and calculated central venous oxygen saturation in critically ill patients

Autor: Malcolm Lemyze, Malligere Prasanna, Laurent Tronchon, Didier Thevenin, Bruno De Oliveira, Jihad Mallat
Rok vydání: 2018
Předmět:
Male
Critical Care and Emergency Medicine
Physiology
lcsh:Medicine
Pathology and Laboratory Medicine
01 natural sciences
Biochemistry
010104 statistics & probability
Hemoglobins
0302 clinical medicine
Cohen's kappa
Mathematical and Statistical Techniques
Medicine and Health Sciences
Cutoff
Central Venous Catheters
Oximetry
lcsh:Science
education.field_of_study
Multidisciplinary
Physics
Statistics
Classical Mechanics
Venous blood
Middle Aged
Shock
Septic
Hospitals
Body Fluids
Chemistry
Intensive Care Units
Blood
Shock (circulatory)
Physical Sciences
Regression Analysis
Female
medicine.symptom
Anatomy
Research Article
Chemical Elements
Correlation coefficient
Critical Illness
Resuscitation
Partial Pressure
Population
Linear Regression Analysis
Research and Analysis Methods
Veins
03 medical and health sciences
Signs and Symptoms
Diagnostic Medicine
Sepsis
medicine
Pressure
Humans
Hemoglobin
0101 mathematics
Statistical Methods
education
Aged
Receiver operating characteristic
business.industry
Septic shock
Pulmonary Gas Exchange
lcsh:R
Biology and Life Sciences
Proteins
030208 emergency & critical care medicine
medicine.disease
Oxygen
Health Care
Health Care Facilities
lcsh:Q
Blood Gas Analysis
Nuclear medicine
business
Mathematics
Zdroj: PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206868 (2018)
ISSN: 1932-6203
Popis: BACKGROUND:Central venous oxygen saturation (ScvO2) is often used to help to guide resuscitation of critically ill patients. The standard gold technique for ScvO2 measurement is the co-oximetry (Co-oximetry_ScvO2), which is usually incorporated in most recent blood gas analyzers. However, in some hospitals, those machines are not available and only calculated ScvO2 (Calc_ScvO2) is provided. Therefore, we aimed to investigate the agreement between Co-oximetry_ScvO2 and Calc_ScvO2 in a general population of critically ill patients and septic shock patients. METHODS:A total of 100 patients with a central venous catheter were included in the study. One hundred central venous blood samples were collected and analyzed using the same point-of-care blood gas analyzer, which provides both the calculated and measured ScvO2 values. Bland and Altman plot, intra-class correlation coefficient (ICC), and Cohen's Kappa coefficient were used to assess the agreement between Co-oximetry_ScvO2 and Calc_ScvO2. Multiple linear regression analysis was performed to investigate the independent explanatory variables of the difference between Co-oximetry_ScvO2 and Calc_ScvO2. RESULTS:In all population, Bland and Altman's analysis showed poor agreement (+4.5 [-7.1, +16.1]%) between the two techniques. The ICC was 0.754 [(95% CI: 0.393-0.880), P< 0.001], and the Cohen's Kappa coefficient, after categorizing the two variables into two groups using a cutoff value of 70%, was 0.470 (P
Databáze: OpenAIRE
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