Global and regional left ventricular myocardial deformation measures by magnetic resonance feature tracking in healthy volunteers: comparison with tagging and relevance of gender
| Autor: | Harald Becher, Daniel Augustine, Steffen E. Petersen, Paul Leeson, Merzaka Lazdam, Aitzaz Bin Sultan Rai, Saul G. Myerson, Adam J. Lewandowski, A. Noble, Stefan Neubauer, Jane M Francis |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Coefficient of variation Magnetic Resonance Imaging Cine 030204 cardiovascular system & hematology Deformation (meteorology) Myocardial velocity Ventricular Function Left 030218 nuclear medicine & medical imaging Strain 03 medical and health sciences Young Adult 0302 clinical medicine Nuclear magnetic resonance Sex Factors Tagging Predictive Value of Tests Healthy volunteers Image Interpretation Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Medicine(all) Observer Variation Reproducibility Analysis of Variance Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Research Myocardial displacement Reproducibility of Results Magnetic resonance imaging Steady-state free precession imaging Myocardial Contraction Biomechanical Phenomena Feature tracking Cardiovascular magnetic resonance Female Cardiology and Cardiovascular Medicine business Nuclear medicine Radial stress Software |
| Zdroj: | Journal of Cardiovascular Magnetic Resonance |
| DOI: | 10.1186/1532-429x-15-8 |
| Popis: | Background Feature Tracking software offers measurements of myocardial strain, velocities and displacement from cine cardiovascular magnetic resonance (CMR) images. We used it to record deformation parameters in healthy adults and compared values to those obtained by tagging. Methods We used TomTec 2D Cardiac Performance Analysis software to derive global, regional and segmental myocardial deformation parameters in 145 healthy volunteers who had steady state free precession (SSFP) cine left ventricular short (basal, mid and apical levels) and long axis views (horizontal long axis, vertical long axis and left ventricular out flow tract) obtained on a 1.5 T Siemens Sonata scanner. 20 subjects also had tagged acquisitions and we compared global and regional deformation values obtained from these with those from Feature Tracking. Results For globally averaged measurements of strain, only those measured circumferentially in short axis slices showed reasonably good levels of agreement between FT and tagging (limits of agreement −0.06 to 0.04). Longitudinal strain showed wide limits of agreement (−0.16 to 0.03) with evidence of overestimation of strain by FT relative to tagging as the mean of both measures increased. Radial strain was systematically overestimated by FT relative to tagging with very wide limits of agreement extending to as much as 100% of the mean value (−0.01 to 0.23). Reproducibility showed similar relative trends with acceptable global inter-observer variability for circumferential measures (coefficient of variation 4.9%) but poor reproducibility in the radial direction (coefficient of variation 32.3%). Ranges for deformation parameters varied between basal, mid and apical LV levels with higher levels at base compared to apex, and between genders by both FT and tagging. Conclusions FT measurements of circumferential but not longitudinally or radially directed global strain showed reasonable agreement with tagging and acceptable inter-observer reproducibility. We record provisional ranges of FT deformation parameters at global, regional and segmental levels. They show evidence of variation with gender and myocardial region in the volunteers studied, but have yet to be compared with tagging measurements at the segmental level. |
| Databáze: | OpenAIRE |
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