Antibodies to Nucleic Acids in Myasthenia gravis
| Autor: | W. K. Engel, Alfred D. Steinberg, M E Gershwin, Ringel Sp, Bender An, Glinski W |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Adult
Male Adolescent T-Lymphocytes Immunology Binding Competitive chemistry.chemical_compound Immune system Myasthenia Gravis Humans Immunology and Allergy Medicine Aged Autoantibodies Acetylcholine receptor biology business.industry Muscles Autoantibody DNA General Medicine Middle Aged medicine.disease Acetylcholine Myasthenia gravis chemistry Nucleic acid biology.protein Female Antibody business medicine.drug |
| Zdroj: | International Archives of Allergy and Immunology. 51:245-252 |
| ISSN: | 1423-0097 1018-2438 |
| DOI: | 10.1159/000231597 |
| Popis: | An increased frequency of antibodies to native DNA, thymocytes, and striated muscle was found in patients with myasthenia gravis (MG). The prevalence of such antibodies lends considerable support to the concept of MG as an autoimmune disorder and militates in favor of major abnormalities in the thymic dependent immune system. There was no correlation between serum-blocking activity to acetylcholine receptor protein and antibodies to thymocytes. |
| Databáze: | OpenAIRE |
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