Serum vascular endothelial growth factor in patients with head and neck squamous cell carcinoma
| Autor: | K. Anyanwu, S. R. Ell, J. Greenman, J.J. Homer, N D Stafford |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Gene isoform
Male Pathology medicine.medical_specialty Angiogenesis VEGF receptors medicine.medical_treatment Tumour stage chemistry.chemical_compound Medicine Humans In patient Growth Substances Aged Neoplasm Staging biology business.industry medicine.disease Head and neck squamous-cell carcinoma Vascular endothelial growth factor Cytokine Otorhinolaryngology chemistry Head and Neck Neoplasms biology.protein Carcinoma Squamous Cell Female Endothelium Vascular business |
| Zdroj: | Clinical otolaryngology and allied sciences. 24(5) |
| ISSN: | 0307-7772 |
| Popis: | Vascular endothelial growth factor (VEGF) is a key pro-angiogenic cytokine expressed by most human tumours. Two isoforms, VEGF121 and VEGF165, are soluble and can be assayed in serum. Serum VEGF has been shown to be significantly raised in patients with solid tumours and shows some promise as a potentially useful tumour marker. Serum levels of VEGF were assayed in 52 patients with untreated head and neck squamous cell carcinoma (HNSCC) and 104 healthy controls. Serum VEGF is significantly raised in patients with HNSCC (P |
| Databáze: | OpenAIRE |
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