Optical trapping assisted detection rate enhancement of single molecules on a nanopore optofluidic chip

Autor:	Aaron R. Hawkins, M. Harrington, Mohammad Julker Neyen Sampad, M. A. Stott, M. Rahman, T. D. Yuzvinsky, Holger Schmidt, Yucheng Li
Rok vydání:	2019
Předmět:	Materials science business.industry Chip Article Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials Dna detection Nanopore Optical tweezers Fiber laser Molecular targets Molecule Optoelectronics Detection rate business
Zdroj:	Optica
ISSN:	2334-2536
Popis:	We use optical trapping to deliver molecular targets to the vicinity of a nanopore for high-throughput single molecule analysis on an optofluidic chip. DNA detection rates increase over 80× to enable detection at attomolar concentrations.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3f65c665529bc25c68de8eaa1daaf6 https://doi.org/10.1364/optica.6.001130 Zobrazit plný text záznamu