Differences in circulating appetite-related hormone concentrations between younger and older adults: a systematic review and meta-analysis
| Autor: | Adrian Holliday, Kelsie Olivia Johnson, Kevin Deighton, Theocharis Ispoglou, Oliver M. Shannon, Jamie Matu |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Aging medicine.medical_specialty Hunger medicine.medical_treatment media_common.quotation_subject Appetite Review Anorexia Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine Humans Medicine 030212 general & internal medicine Aged media_common business.industry Insulin Leptin Fasting Postprandial Period Hormones Anorexia of ageing Postprandial Endocrinology Ageing Anorectic Energy intake Geriatrics and Gerontology medicine.symptom business 030217 neurology & neurosurgery Hormone |
| Zdroj: | Aging Clinical and Experimental Research |
| ISSN: | 1720-8319 1594-0667 |
| DOI: | 10.1007/s40520-019-01292-6 |
| Popis: | Ageing is associated with reduced appetite and energy intakes. However, the mechanisms underlying this phenomenon are not fully understood. This systematic review and meta-analysis quantified differences in circulating concentrations of appetite-related hormones between healthy older and younger adults. Six databases were searched through 12th June 2018 for studies that compared appetite-related hormone concentrations between older and younger adults. Data were pooled using random-effects meta-analysis and are presented as standardised mean difference (Hedges’ g) with 95% confidence intervals (95% CI). Thirty-five studies were included involving 710 older adults (mean ± SD; age: 73 ± 5 years) and 713 younger adults (age: 28 ± 7 years). Compared with younger adults, older adults exhibited higher fasted and postprandial concentrations of the anorectic hormones cholecystokinin (Fasted: SMD 0.41 (95% CI 0.24, 0.57); p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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