Delayed and Overlooked Diagnosis of an Unusual Opportunistic Infection in a Renal Transplant Recipient: Visceral Leishmaniasis
| Autor: | Sule Colakoglu, Tuba Turunç, Soner Solmaz, Aysegul Zumrutdal, Yusuf Ziya Demiroglu, Ertugrul Erken, Ruya Ozelsancak |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Delayed Diagnosis Opportunistic infection Antiprotozoal Agents Opportunistic Infections Immunocompromised Host Bone Marrow Recurrence Amphotericin B medicine Humans Kidney transplantation medicine.diagnostic_test business.industry Biopsy Needle General Medicine medicine.disease Kidney Transplantation Pancytopenia Surgery Transplantation Bone marrow examination medicine.anatomical_structure Visceral leishmaniasis Liposomes Leishmaniasis Visceral Bone marrow business medicine.drug |
| Zdroj: | Turkish Journal of Parasitology. 34:183-185 |
| ISSN: | 1300-6320 |
| DOI: | 10.5152/tpd.2010.09 |
| Popis: | Visceral leishmaniasis is a rare opportunistic infection in renal transplantation patients and its presentation may be associated with or masked by many other factors in immunosuppressed patients. So, if it is not searched for in particular, diagnosis may be easily overlooked or delayed in renal transplant patients. A 32-year-old renal transplant recipient devoleped splenomegaly, pyrexia and pancytopenia. Six months after the first bone marrow examination, the delayed diagnosis was made possible by a second bone marrow aspiration. Liposomal amphotericin B was effective in his treatment although he had a recurrence. Early diagnosis of visceral leishmaniasis is crucial for the renal transplant recipient's therapy; and even in treated patients, the mortality rate may be high. In our case, although the time up to diagnosis was as long as six months after the onset of symptoms, response to treatment was satisfactory with higher doses of liposomal amphotericin B in the second cycle. Also, in the short term, the rate of recurrence was comparable to other reported patients who were diagnosed and treated in a month. |
| Databáze: | OpenAIRE |
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