Fabrication and characterization of β-cypermethrin-loaded PLA microcapsules prepared by emulsion-solvent evaporation: loading and release properties
| Autor: | Jianguo Feng, David Julian McClements, Shengwei Zhang, Seid Mahdi Jafari, Guantian Yang, Qi Liu |
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| Rok vydání: | 2018 |
| Předmět: |
Vinyl alcohol
Materials science Polyesters Health Toxicology and Mutagenesis Capsules 02 engineering and technology 010501 environmental sciences 01 natural sciences Polyvinyl alcohol chemistry.chemical_compound Polylactic acid Pyrethrins Technology Pharmaceutical Environmental Chemistry Particle Size 0105 earth and related environmental sciences Drug Carriers Methylene Chloride General Medicine 021001 nanoscience & nanotechnology Pollution Controlled release Polyester Solvent Kinetics chemistry Chemical engineering Polyvinyl Alcohol Solvents Emulsions Particle size Volatilization 0210 nano-technology Drug carrier |
| Zdroj: | Environmental Science and Pollution Research. 25:13525-13535 |
| ISSN: | 1614-7499 0944-1344 |
| Popis: | Microcapsulses can be designed to effectively encapsulate, protect, and control the release of pesticides. In this study, emulsion-solvent evaporation method was used to fabricate microcapsules using dichloromethane as the solvent, polylactic acid (PLA) as the carrier materials, poly(vinyl alcohol) as the emulsifier, and β-cypermethrin as the entrapped pesticide. The effects of process parameters on the microcapsules characteristics (size, loading content, and encapsulation efficiency) were investigated. Also, the release behavior of the β-cypermethrin was measured experimentally and modeled mathematically. Kinetic analysis indicated that release mechanism of β-cypermethrin was compatible to Fickian diffusion. By optimizing the process parameters, β-cypermethrin-loaded microcapsules were successfully produced with spherical shape, smooth surface, high encapsulation efficiency (> 80%), and a range of pesticide contents. These parameters could be adjusted to achieve delivery systems with desirable release profiles. The results are beneficial to develop delivery systems for rational and effective usage of pesticides. |
| Databáze: | OpenAIRE |
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