| Autor: |
Merkx, Remco, de Bruin, G., Kruithof, Art, van den Bergh, T., Snip, E., Lutz, M., El Oualid, F., Ovaa, H., Crystal and Structural Chemistry, Sub Crystal and Structural Chemistry |
| Přispěvatelé: |
Crystal and Structural Chemistry, Sub Crystal and Structural Chemistry |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Chemical Science, 4(12), 4494. Royal Society of Chemistry |
| ISSN: |
2041-6520 |
| Popis: |
We developed a scalable synthesis of γ-thiolysine starting straight from lysine. The application of γ-thiolysine was compared to δ-thiolysine in the chemical synthesis of K48 and K33 linked diubiquitin conjugates. Both γ- and δ-thiolysine were found to perform equally efficiently as handles for non-enzymatic ubiquitination. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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