ADVANCED CANCER OF THE URINARY BLADDER
| Autor: | J. B. Wear, F. J. Ansfield, R. W. Edland |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
medicine.medical_specialty
Urinary system medicine.medical_treatment law.invention Randomized controlled trial law medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Urinary bladder business.industry General Medicine Radiotherapy alone Advanced cancer Surgery Radiation therapy Cobalt Isotopes medicine.anatomical_structure Urinary Bladder Neoplasms Fluorouracil Concomitant Female Radioisotope Teletherapy business medicine.drug |
| Zdroj: | American Journal of Roentgenology. 108:124-129 |
| ISSN: | 1546-3141 0361-803X |
| DOI: | 10.2214/ajr.108.1.124 |
| Popis: | During the period March 1962 through December 1966, 36 patients were entered into a prospectively randomized study to evaluate the effects of concomitant 5-FU therapy upon the radical supervoltage radiotherapy of advanced invasive carcinoma of the urinary bladder.Despite the almost uniform transient increase in acute morbidity with the combined therapy technique employed in this study, no significant increase in long-term morbidity was encountered over those patients receiving only radical supervoltage radiotherapy.This certainly would be an acceptable price to pay if indeed survival figures were enhanced by these techniques. However, despite the apparent reduction in demonstrable distant metastases utilizing the techniques of drug administration previously outlined, the results of this study, while fully comparable with other surgical series, although preserving bladder function, do not indicate any significant improvement in over-all patient survival when concomitant 5-FU is added to full-dose radical s... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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