Quality of life in patients after radical cystectomy with modified ureterocutaneostomy and Bricker urinary diversion
| Autor: | O. Stakhovskyi, O.A. Voylenko, S. L. Semko, O. A. Kononenko, M. V. Pikul, I. Vitruk, E. O. Stakhovsky, B O Grechko |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Time Factors medicine.medical_treatment Urinary system Urinary Diversion Cystectomy Quality of life Outcome Assessment Health Care medicine Humans Stage (cooking) Perioperative Period Aged Retrospective Studies Bladder cancer business.industry Urinary diversion Disease Management Retrospective cohort study Perioperative Middle Aged medicine.disease Combined Modality Therapy Surgery Treatment Outcome Oncology Urinary Bladder Neoplasms Health Care Surveys Quality of Life Female business Ukraine |
| Zdroj: | Experimental oncology. 42(3) |
| ISSN: | 1812-9269 |
| Popis: | Background Radical cystectomy (RC) has been used for over 100 years as an effective treatment of muscle invasive bladder cancer (MIBC). However, the main surgical challenge is not only to remove an affected organ but also to replace its functional component - urine diversion. The aim of our work is to study the efficacy of the modified ureterocutaneostomy technique by estimating the quality of life in post-RC patients with MIBC. Materials and methods A retrospective analysis of the cases of 40 patients was provided. Two groups were delineated depending on urinary diversion: 20 patients with urinary derivation by the modified ureterocutaneostomy method, and 20 patients - with Bricker conduit. All patients were matched by mean age, gender, American Society of Anesthesiologists status, disease stage and duration. 16 (80%) and 15 (75%) patients from the study and control groups, respectively, passed 3 courses of standard preoperative polychemotherapy with gemcitabine-cisplatin. Quality of life was assessed using the health survey SF-36 form (developed at the US Medical Research Institute), adapted at the National Cancer Institute (Ukraine). Results Comparing patients after ureterocutaneostomy or Bricker surgery, no statistical discrepancy was noted before surgery and after 3 months. A statistical difference in perioperative parameters was noted only when comparing the surgery duration and length of stay in hospital. Conclusions The modified ureterocutaneostomy technique contributes to performing surgery faster and more effectively since an intestinal stage is skipped in surgery. Our findings indicate that ureterocutaneostomy technique may be used as a standard of care for post-RC patients with MIBC. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|