The actions of some putative neurotransmitters on the cockroach salivary gland
| Autor: | C. R. House, F. Bowser-Riley |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Atropine
Serotonin medicine.medical_specialty Carbachol Epinephrine Physiology Dopamine Cockroaches Aquatic Science Biology Salivary Glands Membrane Potentials Norepinephrine Glutamates Internal medicine biology.animal medicine Animals Amino Acids Octopamine Molecular Biology gamma-Aminobutyric Acid Ecology Evolution Behavior and Systematics Neurotransmitter Agents Cockroach Dose-Response Relationship Drug Salivary gland Glutamate receptor Resting potential Acetylcholine Electric Stimulation medicine.anatomical_structure Endocrinology Insect Science Dopamine Antagonists Animal Science and Zoology Octopamine (neurotransmitter) medicine.drug |
| Zdroj: | Journal of Experimental Biology. 64:665-676 |
| ISSN: | 1477-9145 0022-0949 |
| DOI: | 10.1242/jeb.64.3.665 |
| Popis: | Certain putative transmitters were applied to the innervated cockroach salivary gland and their effects on the resting potential and the neurally evoked secretory potential of the acinar cells were observed. γ-Aminobutyric acid, glutamate, glycine, aspartate and alanine had no significant effect on the resting potential. However, γ-aminobutyric acid and glutamate reduced the neurally evoked secretory potential but only at concentrations above 10−3 M. Acetylcholine and carbachol appeared to act by modifying transmitter output from the salivary nerves. These substances failed to have any effect on the resting potential. The biogenic amines, adrenaline, dopamine, noradrenaline, 5-hydroxy-tryptamine and octopamine, produced hyperpolarizing responses, graded according to concentration, It is suggested that dopamine, the most potent of the biogenic amines tested, is the transmitter at this junction. |
| Databáze: | OpenAIRE |
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