Lesões pulmonares provocadas pela nicotina por via subcutânea em ratos
| Autor: | Keyla Ferreira Borges da Rocha, Ítalo Medeiros Azevedo, Aldo Cunha Medeiros, Antônio Medeiros Dantas Filho, Tertuliano Aires Neto |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Pathology Lung RD1-811 business.industry Nicotina Pulmões Group ii lcsh:Surgery lcsh:RD1-811 Bronchopneumonia Placebo medicine.disease Gastroenterology Via subcutânea Nicotine medicine.anatomical_structure Internal medicine Medicine Surgery business Pulmoes Subcutaneous use medicine.drug |
| Zdroj: | Acta Cirurgica Brasileira, Vol 18, Iss suppl 1, Pp 24-27 (2003) Acta Cirurgica Brasileira, Vol 18, Iss suppl.1, Pp 24-27 (2003) Repositório Institucional da UFRN Universidade Federal do Rio Grande do Norte (UFRN) instacron:UFRN Acta Cirúrgica Brasileira v.18 suppl.1 2003 Acta Cirúrgica Brasileira Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC |
| ISSN: | 0102-8650 |
| DOI: | 10.1590/s0102-86502003000700005 |
| Popis: | Objective : The aims of this study were to determine and quantify the influence ofnicotine, applied subcutaneously, in the lungs of rats. Methods : Twenty Wistar rats weighing235–35g were randomly separated in two groups. The group I (n=10) received nicotine ( 2 mg/Kgbody mass/day) during 20 days and the group II (n=10) received placebo subcutaneously. Results :The results illustrate that in the group I resulted bronchopneumonia in 3 (30%) rats, alveolarleucocitosis in 10 (100%), septal leucocitosis in 7 (70%) and atelectasia was found in 2 (20%).Transformed in scores, the data totalized 52 points. The scores of the lesions observed in the lungsof group II rats reached 11 points (p |
| Databáze: | OpenAIRE |
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