Hydroxymethoxybenzoylmethylecgonines: new metabolites of cocaine from human urine
| Autor: | Michael A. Poquette, R. Martin Smith, Paula J. Smith |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Male Chemical Health and Safety Chromatography Chromatography Gas Chemistry Health Toxicology and Mutagenesis Metabolite Metabolism Urine Emergency treatment Toxicology Mass Spectrometry Analytical Chemistry chemistry.chemical_compound Cocaine Mass spectrum Structural isomer Environmental Chemistry Humans Cocaine metabolites Female Gas chromatography |
| Zdroj: | Journal of analytical toxicology. 8(1) |
| ISSN: | 0146-4760 |
| Popis: | 4'-Hydroxy-3'-methoxybenzoylecgonine methyl ester (IIIe) and 3'-hydroxy-4'-methoxybenzoylecgonine methyl ester (IIId) were identified as cocaine metabolites in the urine of an admitted habitual polydrug user. The mass spectra and relative gas-liquid chromatography retention times of these metabolites were compared with those of five synthesized hydroxymethoxycocaine positional isomers. IIIe was also identified by mass chromatography in the urine of three patients who received emergency treatment for cocaine abuse. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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