Risk for neural tube defect-affected pregnancies among women of Mexican descent and white women in California
| Autor: | C R Wasserman, E M Velie, Gary M. Shaw |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Population California White People Pregnancy Risk Factors Mexican Americans Epidemiology medicine Humans Neural Tube Defects Risk factor education education.field_of_study Neural tube defect business.industry Obstetrics Infant Newborn Public Health Environmental and Occupational Health Neural tube Social Support Odds ratio medicine.disease Confidence interval medicine.anatomical_structure Socioeconomic Factors Case-Control Studies Female business Maternal Age Research Article |
| Zdroj: | American Journal of Public Health. 87:1467-1471 |
| ISSN: | 1541-0048 0090-0036 |
| DOI: | 10.2105/ajph.87.9.1467 |
| Popis: | OBJECTIVES: This study investigated a previously reported 50% or more increased risk for neural tube defect-affected pregnancies among Latina women compared with White women. METHODS: Data were derived from a population-based case-control study of fetuses and live-born infants with neural tube defects in a 1989-through-1991 California birth cohort. Interviews were conducted with mothers of 538 (88% of eligible) infants/fetuses with neural tube defects and mothers of 539 (88%) nonmalformed control infants. RESULTS: The risk for a neural tube defect-affected pregnancy was approximately twice as high among women of Mexican descent than among White women (odds ratio = 1.9, 95% confidence interval [CI] = 1.5, 2.8). The odds ratio for Mexico-born Mexican women compared with White women was 2.4 (95% CI = 1.7, 3.2), whereas the risk for US-born women of Mexican and other racial/ethnic descent was not substantially higher than that for Whites. The higher risk among Mexico-born Mexican women was not attributable to differences in numerous studied parental characteristics and exposures. CONCLUSIONS: Given that nearly 20% of all California births are to Mexico-born Mexican women, the increased risks observed are relevant to the population burden of neural tube defects. |
| Databáze: | OpenAIRE |
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