Mood Disorders in Levothyroxine-Treated Hypothyroid Women
| Autor: | Blanca Notario-Pacheco, Benjamín Romero-Gómez, Juan Manuel Carmona-Torres, Paula Guerrero-Alonso, Ana Isabel Cobo-Cuenca |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Pediatrics medicine.medical_specialty endocrine system endocrine system diseases Health Toxicology and Mutagenesis levothyroxine Levothyroxine 030209 endocrinology & metabolism Hospital Anxiety and Depression Scale Article 03 medical and health sciences 0302 clinical medicine Hypothyroidism Surveys and Questionnaires medicine Prevalence Humans 030212 general & internal medicine Depression (differential diagnoses) Health professionals business.industry Mood Disorders Public Health Environmental and Occupational Health medicine.disease Thyroxine Mood Mood disorders Case-Control Studies Anxiety Female women medicine.symptom business Weight gain hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | International Journal of Environmental Research and Public Health Volume 16 Issue 23 |
| ISSN: | 1660-4601 1661-7827 |
| Popis: | Background: Hypothyroidism has several symptoms (weight gain, arrhythmias, mood changes, etc.). The aims of this study were (1) to assess the prevalence of anxiety and depression in levothyroxine-treated hypothyroid women and in women without hypothyroidism (2) to identify variables associated with anxiety and depression. Methods: A case-control study was performed with 393 women. Case-group: 153 levothyroxine-treated hypothyroid women. Control-group: 240 women without hypothyroidism. Convenience sampling. Instrument: The Hamilton Hospital Anxiety and Depression Scale (HADS), and a sociodemographic questionnaire. Results: The prevalence of anxiety in levothyroxine-treated hypothyroid women was higher than in women without hypothyroidism (29.4% vs. 16.7%, &chi 2 p < 0.001). The prevalence of depression in the case group was higher than in the control group (13.1% vs. 4.6%, &chi 0.001). Levothyroxine-treated hypothyroid women were more likely to have anxiety (OR = 2.08, CI: 1.28&ndash 3.38) and depression (OR = 3.13, IC = 1.45&ndash 6.45). Conclusion: In spite of receiving treatment with levothyroxine, women with hypothyroidism are more likely to have depression and anxiety. Health professionals need to assess the mood of women with hypothyroidism. Although levothyroxine is a good treatment for the symptoms of hypothyroidism, it may not be enough to prevent development or persistence of depression and anxiety by itself. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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