Isolated cervical lymph node sarcoidosis: a diagnostic challenge of a case report

Autor: Chee Chean Lim, Sakina Ghauth, Yew Toong Liew, Mohd Zukiflee bin Abu Bakar, Prepageran A. L. Narayanan
Rok vydání: 2023
Předmět:
Zdroj: European Archives of Oto-Rhino-Laryngology. 280:925-927
ISSN: 1434-4726
0937-4477
Popis: Sarcoidosis is a granulomatous disorder involving multi-systemic organs. Patients invariably have lung involvement but some may have extrapulmonary disease. Rarely, cervical lymphadenopathy is the only sign without mediastinal or pulmonary abnormalities.We report a Malay male who complained of neck swelling exclusively. On imaging, multiple enlarged cervical lymph nodes deep to the sternocleidomastoid muscle were seen. An excision biopsy revealed non-caseating granulomas with epithelioid macrophages. Extensive investigations led to the diagnosis of isolated cervical lymph node sarcoidosis.Sarcoidosis can present as cervical lymphadenopathy alone, without mediastinal or lung disease. The presence of epithelioid granulomas on histopathology warrants the exclusion of other granulomatous diseases. Isolated cervical lymph node sarcoidosis is only diagnosed in the presence of consistent clinical and radiological findings. In this case, close monitoring for systemic sarcoidosis is important as it can manifest later in life.
Databáze: OpenAIRE