Os(ii) complexes for catalytic anticancer therapy: recent update

Autor:	Rajesh Kushwaha, Ashish Kumar, Souvik Saha, Sumit Bajpai, Ashish Kumar Yadav, Samya Banerjee
Rok vydání:	2022
Předmět:	Coordination Complexes Pyruvic Acid Materials Chemistry Metals and Alloys Ceramics and Composites Humans Antineoplastic Agents General Chemistry NAD Reactive Oxygen Species Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials
Zdroj:	Chemical Communications. 58:4825-4836
ISSN:	1364-548X 1359-7345
DOI:	10.1039/d2cc00341d
Popis:	The recent dramatic enhancement in cancer-related mortality and the drawbacks (side effects and resistance) of Pt-based first-generation chemotherapeutics have escalated the need for new cancer medicines with unique anticancer activities for better human life. To overcome the demerits of Pt-based cancer drugs, the concept of catalytic anticancer agents has recently been presented in the field of anticancer metallodrug development research. Many intracellular transformations in cancer cells are catalyzed by metal complexes, including pyruvate reduction to lactate, NAD(P)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0b35e6f7850c0b38bcd875d32c83a3 https://doi.org/10.1039/d2cc00341d Zobrazit plný text záznamu