Association of Selected Adipocytokines and Inflammatory Markers on Body Mass Index in Type 2 Diabetes Patients in Saudi Arabia and as Risk Factors to Cardiovascular Disease
| Autor: | Sultan Mohammed Namis, Youssef Jadallah Bajnaid, Sapna B. Shetty, Prabu Mahin Syed Ismail, Antony A. Anandaraj, Khalid M. Almutairi |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Endocrinology Diabetes and Metabolism Adipokine Type 2 diabetes Overweight Body Mass Index 03 medical and health sciences 0302 clinical medicine Endocrinology Adipokines Risk Factors Internal medicine Diabetes mellitus medicine Humans Obesity Prospective Studies Inflammation Adiponectin business.industry nutritional and metabolic diseases Middle Aged medicine.disease 030104 developmental biology Diabetes Mellitus Type 2 Cardiovascular Diseases 030220 oncology & carcinogenesis Female Resistin medicine.symptom business Body mass index Biomarkers |
| Zdroj: | Current Diabetes Reviews. 13:330-335 |
| ISSN: | 1573-3998 |
| Popis: | Introduction: In this prospective study, we establishing the association of obesity in type 2 diabetes patients with various inflammatory markers and adipocytokines, as risk factors for cardiovascular disease (CVD). Materials and Methods: In this work, a total of 85 individuals gave concern and were divided into 4 groups based on their body mass indices (BMI). Anthropometrics details were obtained from each individual and different laboratory tests were performed to measure levels of adipocytokines such as adiponectin, leptin and resistin and inflammatory markers such as TNF-α, IL-6 and hsCRP. All the 82 patients with T2D were studied in four groups, A includes obese with BMI >30 kg/m2, B includes overweight with BMI ranging 25 to 30 kg/m2), C includes non-obese with BMI< 25 kg/m2. Group D was control, included non-obese (BMI< 25 kg/m2) and non-diabetic individuals. Result & Discussion: There was an increase in plasma insulin levels in T2D patients, especially with exhibiting high BMI and diabetic conditions in Group A. Adiponectin was higher in the control group which is significant with the value of p |
| Databáze: | OpenAIRE |
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