Risk factors for death, stroke, and bleeding in 28,628 patients from the GARFIELD-AF registry: Rationale for comprehensive management of atrial fibrillation

Autor:	Ibrahim, M., Erga, K., Hole, T., Gjertsen, E., Kirchner-Volker, K., Hubert, K., Helgert, K., Hahn, M., Grytzmann, A., Geyer, J., Gehre, J., Frommhold, R., Fritz, C., Floegel, H., Flint, K., Fleck, A., Diez, S., Dichristin, U., Busch, F., Buckert, D., Bonin, K., Boehme, S., Bergner, K., Babjakova, Z., Mitrovic, V, Mueller, H., Mueller, T., Erdle, W., Schoen, S., Roehnisch, J-U, Salbach, P., Haverkamp, W., Sievers, B., Karolyi, L., Bernhardt, P., Schellong, S., Schwencke, C., Ebert, H-H, Baumbach, S., Abdel-Qader, M., Mueller, K., Kamin, S., Brauer, G., Buchner, T., Lauer, H., Schubert, C., Kolitsch, K., Lilienweiss, V, Leuchtgens, H., Hey, H., Eissing, V, Horstmeier, U., Mayer, P., Vormann, R., Rapp, K-A, Michel, H., Dshabrailov, J., Dorsch, W., Hauk, J., Reimer, D., Hergdt, G., Bindig, H-W, Lehmann, G., Hartmann, H-J, Laessig, T., Omankowsky, S., Caspar, A., Kahl, F., Kropp, M., Zimny, H-H, Stuchlik, G., Babyesiza, A., Schwarz, T., Axthelm, C., Wildenauer, W., Wiswedel, H., Ludwig, N., Sandow, P., Pustelnik, A., Menke, H., Guenoun, M., Boveda, S., Cebron, J-P, Delarche, N., Piot, O., Destrac, S., Marquand, A., Koujan, M. B., Muller, J-J, Loiselet, P., Paganelli, F., Gottwalles, Y., Galinier, M., Le Heuzey, J-Y, Vasankari, T., Rasanen, V, Peltomaki, K., Nappila, H., Koistinen, J., Arola, O., Airaksinen, J., Raatikainen, P., Vesterager, K., Tilma, J., Therkelsen, A., Schou, M., Park, J., Nygaard, A., Leth, M., Jensen, M., Jensen, L., Eriksen, E., Ellervik, C., Bang-Hansen, T., Raymond, I, Ibsen, H., Egstrup, K., Skagen, K., Dominguez, H., Mertz, J., Bruun, M., Loekkegaard, T., Simonsen, P., Solgaard, J., Boerger, J., Markenvard, J., Bremmelgaard, A., Rasmussen, S., Hintze, U., Husted, S., Nielsen, H., Nielsen, J., Zika, J., Zidek, M., Valtova, M., Sveceny, J., Sulc, A., Prochazkova, E., Potuznik, P., Michalik, D., Majernikova, M., Mahdalikova, L., Ludkova, A., Lubanda, H., Lipoldova, J., Lindourkova, A., Labrova, R., Krcova, E., Kratochvilova, R., Kopeckova, I, Janska, L., Hubacova, V, Horejsi, M., Honek, J., Drasnar, T., Dastychova, L., Chlumsky, J., Bultas, J., Novikova, E., Nagibovich, G., Motylev, I, Monako, G., Medvedeva, T., Machilskaya, O., Lileeva, E., Lebedeva, O., Kolesova, T., Ivanova, Y., Gurmach, M., Gubanov, A., Gorshkova, T., Gorbunova, E., Erofeeva, S., Dumikyan, A., Chugunnaya, S., Bitakova, F., Belenkova, Y., Batalov, R., Agakhanyan, A., Edin, A., Nagibovich, O., Shapovalova, Y., Zubeeva, G., Rossovskaya, M., Sobolev, K., Polkanova, E., Moiseeva, Y., Kostenko, V, Novikova, T., Zrazhevskiy, K., Mazur, E., Shutemova, E., Sergeev, M., Chizhov, P., Aleksandrova, E., Miller, O., Barbarash, O., Vishnevsky, A., Drapkina, O., Zateyshchikov, D., Poltavskaya, M., Yakupov, E., Khokhlov, A., Egorova, L., Nikolaev, K., Kolesnikova, A., Kropacheva, E., Zateyshchikova, A., Belenky, D., Kamalov, G., Popov, S., Tereshchenko, S., Libis, R., Eltishcheva, V, Panchenko, E., Zyczynska-Szmon, M., Zakutynska-Kowalczyk, K., Wrobel, M., Wojnowski, L., Wojewoda, P., Wilgat-Szecowka, M., Wilczewski, P., Wierzbicka, A., Wieczorek, W., Wesolowska, K., Wegrzynowska, M., Walasik, P., Tybura, S., Trzcinski, G., Troszczynska, M., Traczyk, T., Szwoch, M., Szumczyk-Muszytowska, G., Szulowska, A., Szuchnik, E., Szkrobka, W., Szczepanska, A., Szalecki, P., Szafranski, J., Sukiennik-Kujawa, M., Stopyra-Poczatek, M., Starak-Marciniak, J., Staniszewska, E., Staneta, P., Splawski, M., Smichura, M., Skalska, J., Sidor, A., Rzyczkowska, B., Rychta, J., Rozewska-Furmanek, D., Roszczyk, N., Rostoff, P., Romaszkiewicz, R., Romanek, J., Rogowski, W., Raczynska, A., Ptaszynski, P., Piotrowicz, R., Pawlik-Rak, E., Pawelska-Buczen, A., Ozgowicz, M., Opielowska-Nowak, B., Nowak, S., Nowak, A., Niemirycz-Makurat, A., Niedek, J., Neubauer-Geryk, J., Mielcarek, M., Miedlar, E., Metzgier-Gumiela, A., Mazur, M., Markiewicz, A., Mariankowski, R., Majewska, K., Machnikowska, M., Lysek-Jozefowicz, A., Luka, J., Loboz-Rudnicka, M., Lip, K., Lichota, E., Lewicka, E., Leszczynski, J., Lesniewska-Krynska, D., Kustrzycka-Kratochwil, D., Kurdzielewicz, W., Krzyzanowski, M., Poli, D., Cappelli, R., Tessitori, M., Martini, G., Caimi, T. M., Moia, M., Di Minno, G., Testa, S., Santoro, R., Tiraferri, E., Ambrosio, G., Agnelli, G., Vandrus, B., Sztanyik, F., Szilagyi, A., Bockova, L., Antonova, P., Durdil, V, Lastuvka, J., Novak, M., Vitovec, J., Spinar, J., Podrazil, P., Honkova, M., Dedek, V, Petrova, I, Pisova, J., Jerabek, O., Burianova, H., Monhart, Z., Kotik, I, Hubac, J., Ferkl, R., Racz, B., Plocova, K., Kotik, L., Olsr, J., Ludka, O., Zidkova, E., Machova, V, Spacek, R., Reichert, P., Jansky, P., Weyn, T., Vydt, T., Verloove, H., Vergauwen, L., Vantomme, C., Vanhauwaert, B., Vanhalst, E., Vandorpe, A., Vandenbroeck, D., Vandekerckhove, Y., Vandekerckhove, H., Van Lier, D., Van Durme, F., Tincani, G., Thyssen, V, Tahon, S., Stockman, I, Smolders, W., Smessaert, C., Simons, N., Semeraro, O., Scheurwegs, C., Salembier, J., Rombouts, H., Richa, J., Raymenants, E., Raepers, M., Postolache, A., Pollet, P., Piamonte, V, Nimmegeers, J., Mestdagh, I, Lips, S., Jacobs, C., Helvasto, L., Hellemans, S., Gits, F., Ghekiere, M., Feys, E., Eykerman, T., Everaert, M., Drieghe, S., Dormal, F., Deweerd, E., Derycker, K., Denie, D., Delvigne, M., Delforge, M., Leyva Rendon, A., Matadamas Hernandez, N., Cardona Munoz, E., Pozas, G., Llamas Esperon, G., Lopez Rosas, E., Villarreal Umana, S., Espinola Zavaleta, N., Cabrera Jardines, R., Ramos Zavala, M. G., Leal Cantu, R., Illescas Diaz, J., Sanchez Diaz, C. J., Villan, C., Vergara, M., Olguin, V, Munoz Oyarzon, J., Molina, E., Lara, C., Campisto, Y., Aguilar, J., Astudillo, C., Rey, C., Charme Vilches, G., Larico Gomez, M., Lanas, F., Forero, A., Montecinos, H., Marin Cuevas, P., Houzvic, C., Conejeros, C., Stockins Fernandez, B. A. J., Potthoff Cardenas, S., Arriagada, G., Bugueno Gutierrez, C., Eggers, G., Corbalan, R., Villaca Guimaraes Filho, F., Vila Boas, L., Vieira Torres, L. G., Vieira Homem, R., Vidal Armaganijan, L., Vicente, C., Viana, T., Vargas, T., Valois, M. V., Unterkircher, B., Trama, L., Toazza Duda, N., Stoll, C., Spolaor, L., Soares, L., Silva, S., Seroqui, M., Santos, M., Santos, I, Santos, D., Ruaro Reichert, T., Roesch, H., Rodrigues, A., Ribeiro, S., Rech, R. L., Ramos Pereira, N., Queirantes, C., Quaia Fortunato, S. C., Poletti, S., Perreira, R., Pereira, V. L., Pereira, L., Pavani, R., Palmegiani, E., Oss Emmer, S., Ormundo, C., Nanzer Vital, C., Mouco, O. M. C. C., Mortari, L., Melo, G., Mazzoni, M., Kuvanova, M., Kurylo, B., Kupriyanova, T., Kungurtseva, O., Kuchuk, P., Kropova, O., Korneeva, O., Konyushenko, D., Heinz, G-U, Zutz, S., Glatzel, D., Rehling, G., Eder, W., Eissfeller, E., Hohensee, H., Riegel, P., Zauzig, H., Schaefer, T., Kopf, A., Kellner, B-T, Gerbaulet, U., Purr, J., Koeniger, G., Darius, H., Suissa, A., Sanchez, D., Rosolin, N., Robin, F., Lemaire, N., Ledure, S., Kemmel, A., Giry, X., Ducasse, E., Dubois, B., Decarsin, N., Corrihons, E., Beltra, C., Barreau, A., Poulard, J-E, Perron, J-M, Falvo, N., Chemin, F., Berneau, J-B, Casassus, F., Fedorowsky, A., Brugnaux, J. P., Nazeyrollas, P., Bearez, E., Mouallem, J., Crousillat, B., Obadia, D., Martelet, M., Doucet, B., Boyes, J-P, Monniot, G., Sellem, F., Navarre, V, Churet, J-B, Bonnefoy, M., Mielot, A., Mahagne, M. H., Neau, J-P, Sibon, I, Vandamme, X., Milandre, L., Rodier, G., Lemaire, M., Huberman, J-P, Fournier, P-Y, Kadouch, J., Ellie, E., Amarenco, P., Zuber, M., Assouline, S., Ohayon, J., Galley, D., Guedj-Meynier, D., Marinho, M. C., Macagnan, A. P., Lustosa, E., Lourenco da Silva Junior, O., Lopes, D., Lino, E. G., Komar, D., Junior, G., Jannuzzi, F., Igansi, F., Hettwer Magedanz, E., Guizzardi, S., Guanaes, D., Gottardo, P., Freire, F., Franchin Ferraz, R., Frack Costantini, C. R., Fonseca, C., Fernandes, E., Felix Lorenzato Fonseca, T., Fabri, P., Esteves, D. C., Ely Pizzato, P., Drummond Wainstein, A. P., Dias, M. A., Dias, C., Del Monaco, M., de Araujo, G. R., Daros, E., da Silveira, J. A., da Silva Paulitsch, F., da Silva, L. S., Costantini Ortiz, C., Costa, M., Correa, C., Codonho Goes, N., Clemente Mingireanov, R., Chokr, M. O., Chieza, F., Cardoso Boscato, S., Caporale, M., Camazzola, F. E., Borges Queiroz, L., Biazus, G., Benez Teixeira Lemos, M. A., Bellotti Lopes, H., Belisario Falchetto, E., Barroso, S., Barbosa, T., Arruda Nakazone, M., Araujo, V, Alves de Oliveira Gomes, J., Agliardi, P., Gomes Ferreira, L. G., do Carmo Borges, N. C., Simoes de Almeida, R., Nigro Maia, L., Tumelero, R. T., de Moura Xavier Moraes Junior, J. B., Aranha Rosito, G. B., Alban, F., Broilo Franca, C. C., Pereira Martins, M., Chemello, D., Pisani, C., Finimundi, H. C., Abdalla Saad, J., Costantini Frack, C. R., Munhoz da Fontoura Tavares, C., Vieira Botelho, R., Lanna Figueiredo, E., Ramos Filho, R. A., Reis, G., Roquette, F., Bertolim Precoma, D., Moncada, C., Alves da Costa, F. A., Da Rocha Rodrigues, T., Del Carlo, C. H., Westerlund Montera, M., Bodanese, L. C., Menezes Lorga Filho, A., Moura Jorge, J. C., Moreira, D., Pires, L., Ferreira Rossi, P. R., Silveira Teixeira, M., Ribeiro, J. M., de Souza Neto, J. D., Kunz Sebba Barroso de Souza, W., Steffens, A., Faria Neto, J., Armaganijan, D., Jaber, J., Sobral Filho, D. C., Barretto, A. C. P., Zurbrigk, F. J., Zillo, M., Yunis, M. E., Vallejo, M., Tufare, A. L., Tonelli, L., Tinto, J. F., Sossich, A., Schygiel, P. O., Sanziani, L. S., Salinger, M., Said Palladino, M. E., Rolandi, F., Rodriguez, M. A., Ricotti, C., Potito, R. N., Pontoriero, J., Perez Prados, G., Novas, V, Navarro, A., Munguia, R., Meirino, A., Mautner, B., Matkovich, J., Martinelli, C., Martinelli, A., Maffei, L., Maehara, G., Lopez, A., Ingratta, M., Hrabar, A. D., Hansen, V, Had, M. de L. M., Gurfinkel, E. P., Gimenez, C. H., Giacomi, M. P., Funosas, C., Foa Torres, M., Fernandez Voena, F., Fanuele, M., Eden, M. F., Diez, F., De Urquiza, I. N., Damonte, A. A., Costamagna, O. J. A., Costabel, J. P., Colombo Berra, F., Carrizo, R., Cappi, A. L., Campisi, V, Cabrini, R., Buzzetti, C., Borchowiec, S., Berli, M., Berli, F., Bergesio, L., Belardi, J. 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J., Hernandez Herrera, C., Lopez Villezca, D., Virgen Carrillo, L., de los Rios Ibarra, M., Garcia Hernandez, N., Arabetti, C., Alvarez D'Amelio, A., Alaguibe, E. D., Ferroni, F., Gomez Vilamajo, O. A., Berli, M. A., Cartasegna, L. R., Sinisi, V. A., Sassone, S., Fosco, M. J., Fernandez, A. A., Egido, J., Dran, R. D., Ramos, J. L., Di Paola, L. A., Zapata, G., Conde, D., Ahuad Guerrero, R. A., Giacomi, G., Centurion, N., Kleiban, A. J., Dragotto, P., Berman, S. G., Fernandez Caputi, V, Sambadaro, G. A., Ingaramo, A. C., Vensentini, N., Luciardi, H. L., Yuksekdag, V, Yilmaz, F., Yildirim, R., Yildirim, E., Alkan, D. Uzun, Seker, T., Sayin, B. Y., Sahiner, L., Sag, H., Quisi, A., Ozcelik, E., Okutucu, S., Karatas, S. Kilic, Karaayvaz, E. B., Ikitimur, B., Genc, D., Felekoglu, M. A., Esen, M., Oto, A., Caliskan, S., Buyukpapuc, M., Budeyri, S., Bireciklioglu, M. F., Aras, F., Alpay, D., Aktas, O., Abdelrahman, H., Aras, D., Okuyan, E., Ersanli, M., Yorgun, H., Demir, M., Sayin, T., Sucu, M., Ozdemir, M., Pekdemir, H., Cayli, M., Ongen, Z., Yeter, E., Aydinlar, A., Yilmaz, O., Ozdemir, K., Ozdogru, I, Altun, A., Yawila, S., Wutthimanop, A., Wongtheptien, W., Wisaratapong, T., Park, B. R., Park, A. R., Noh, I. K., Lee, W. Y., Lee, S., Lee, S. H., Lee, S. E., Lee, R. W., Lee, M-Y, Lee, M. S., Lee, K. R., Lee, K. H., Lee, H-Y, Lee, H. Y., Lee, G. H., Lee, E. H., Lee, C. S., Kim, Y, Kim, S. H. (Sang Hyun), Kim, S. H. (Sang Hee), Kim, M. S., Kim, K. T., Kim, J. A., Kim, J. S. (Jung Sook), Kim, J. S. (Ji Seon), Kim, H. J. (Hyun Ju), Kim, H. J. (Hyeon Jeong), Jung, I-A, Jeong, H. K., Jeon, Y. R., Jeon, S. R., Jeon, H-G, Jang, S., Jang, H-S, Jang, E. M., Hwang, S. W., Her, K. O., Heo, E. S., Han, S., Choi, H. S., Choi, H. K., Choi, E. H., Choi, E. A., Chi, W. J., Baek, A. L., Bae, H., An, H. J., Ahn, J. J., Kim, D. B., Kim, C-J, Hwang, G-S, Jung, B. 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S., Cheung, S., Leader, R., Beaudry, P., Ayala-Paredes, F., Berlingieri, J., Heath, J., Poirier, G., Du Preez, M., Nadeau, R., Dresser, G., Dhillon, R., Hruczkowski, T., Schweitzer, B., Coutu, B., Angaran, P., MacDonald, P., Vizel, S., Fikry, S., Parkash, R., Lavoie, A., Cha, J., Ramjattan, B., Bonet, J., Ahmad, K., Aro, L., Aves, T., Beaudry, K., Bergeron, C., Bigcanoe, J., Bignell, N., Breakwell, L., Burke, E., Carroll, L., Clarke, B., Cleveland, T., Daheb, S., Dehghani, P., Denis, I, Djaidani, Z., Dorian, P., Douglass, S., Dunnigan, J., Ewert, A., Farquhar, D., Fearon, A., Ferleyko, L., Fournier, D., Fox, B., Grenier, M-C, Gulliver, W., Haveman, K., Hines, C., Hines, K., Jackson, A. M., Jean, C., Jethoo, G., Kahlon, R., Kelly, S., Kim, R., Korley, V, Kornder, J., Kwan, L., Largy, J., Lewis, C., Lewis, S., Mangat, I, Moor, R., Fushtey, I, Belegai, R., Berko, G., Burdeuna, L., Chabanna, O., Daniuk, I, Ivanov, A., Kamenska, E., Kaplan, P., Khyzhnyak, O., Kizim, S., Matova, O., Medentseva, O., Mochonyi, V, Mospan, M., Nemtsova, V, Ovdiienko, T., Palamarchuk, O., Pavelko, M., Petrovskyy, R., Plevak, D., Proshak, O., Pyvovar, S., Rasputina, L., Romanenko, O., Romanova, O., Sapatyi, A., Shumakov, O., Stets, R., Todoriuk, L., Varenov, V., Fitzmaurice, D., Chauhan, N., Goodwin, D., Saunders, P., Evans, R., Leese, J., Jhittay, P. S., Ross, A., Kainth, M. S., Pickavance, G., McDonnell, J., Williams, A., Gooding, T., Wagner, H., Suryani, S., Singal, A., Sircar, S., Bilas, R., Hutchinson, P., Wakeman, A., Stokes, M., Paul, N., Aziz, M., Ramesh, C., Wilson, P., Franklin, S., Fairhead, S., Thompson, J., St Joseph, V, Taylor, G., Tragen, D., Seamark, D., Paul, C., Richardson, M., Jefferies, A., Sharp, H., Jones, H., Giles, C., Page, M., Oginni, O., Aldegather, J., Wetherwell, S., Lumb, W., Evans, P., Scouller, F., Macey, N., Stipp, Y., McLeod, A. J., Poland, K., Mulholland, C., Warke, A., Conn, P., Smith, R. N., Lowe, S., Kamath, R., Dau, H. S., Webster, J., Hodgins, I, Vercoe, S., Roome, P. C., Pinnock, H., Patel, J. R. A., Ali, A., Hart, N., Davies, R., Stuart, E., Neden, C. A., Danielsen, M., Heath, R., Sharma, P., Galloway, S., Hawkins, C., Oliver, R., Aylward, M., Mannion, S., Braddick, M., Edwards, D., Rothwell, A. C., Sabir, A., Choudhary, F., Khalaque, S., Wilson, A., Peters, S., Coulson, W., Roberts, N., Heer, A., Coates, S., Ward, B., Jackson, D., Walton, S., Shepherd, D., Sterry, M., Wong, T., Boon, M., Bunney, R., Haria-Shah, R., Baron, R. T., Davies, S., Schatzberger, T., Hargreaves, N., Stephenson, T., Choi, H., Batson, R., Lucraft, L., Myhill, T., Estifano, S., Geatch, D., Wilkinson, J., Veale, R., Forshaw, K., Davies, T., Zaman, K., Vinson, P., Liley, C., Bandrapalli, M., McGinty, P., Wastling, R., McEleny, P., Beattie, A., Cooke, P., Wong, M., Gunasegaram, J., Pugsley, M., Felpel, S., Ferdinand, K., Fielder, D., Gentry, P., Haideri, A., Hakimi, F., Harbour, T., Hartranft, E., Hawkins, B., Headlee, M., Henson, L., Herrick, C., Hicks, T., Jasinski, S., Jones, A., Jones, L., Jones, P., Karl, S., Keeling, M., Kerr, J., Knowles, P., Langdon, J., Lay, M., Lee, J. A., Lincoln, T., Malone, E., Merliss, A., Merritt, D., Minardo, J., Mooso, B., Orosco, C., Palumbo, V, Parker, M., Parrott, T., Paserchia, S., Pearl, G., Peterson, J., Pickelsimer, N., Purcell, T., Raynor, J., Raziano, S., Richard, C., Richardson, T., Robertson, C., Sage, A., Sanghera, T., Shaw, P., Shoemaker, J., Smith, K., Stephanie, B., Thatcher, A., Theobald, H., Thompson, N., Treasure, L., Tripti, T., Verdi, C., Worthy, V, Ahmad, S., A'Court, C., Ayers, J., Bennett, J., Cartwright, S., Dobson, S., Dooldeniya, C., Flynn, A., Fox, R., Goram, J., Halpin, A., Hay, A., Jacobs, P., Jeffers, L., Lomax, L., Munro, I, Muvva, R., Nadaph, M., Powell, K., Randfield, S., Redpath, D., Reed, R., Rickenbach, M., Rogers, G., Saunders, P. B., Seamark, C., Shewring, J., Simmons, P., Simper, H., Stoddart, H., Sword, A., Thomas, N., Thomson, A., Gibbs, H., Blenkhorn, A., Singh, B., Van Gaal, W., Abhayaratna, W., Lehman, R., Roberts-Thomson, P., Kilian, J., Coulshed, D., Catanchin, A., Colquhoun, D., Kiat, H., Eccleston, D., French, J., Zimmett, L., Ayres, B., Phan, T., Blombery, P., Crimmins, D., O'Donnell, D., Choi, A., Astridge, P., Arstall, M., Jepson, N., Binnekamp, M., Lee, A., Rogers, J., Starmer, G., Carroll, P., Faunt, J., Aggarwala, A., Barry, L., Batta, C., Beveridge, R., Black, A., Bonner, M., Boys, J., Buckley, E., Campo, M., Carlton, L., Connelly, A., Conway, B., Cresp, D., Dimitri, H., Dixon, S., Wong, S., Wright, D., Ragy, H., Abd El-Aziz, A., Abou Seif, S. K., El Din, M. G., El Etriby, S., Elbahry, A., El-Etreby, A., Elkhadem, M., Katta, A., Khairy, T., Mowafy, A., Nawar, M., Ohanissian, A., Reda, A., Reda, M., Salem, H., Sami, N., Samir, S., Setiha, M., Sobhy, M., Soliman, A., Taha, N., Tawfik, M., Zaatout, E., Kettles, D., Bayat, J., Siebert, H., Horak, A., Kelfkens, Y., Garda, R., Pillay, T., Guerra, M., van Zyl, L., Theron, H., Murray, A., Louw, R., Greyling, D., Mntla, P., Ueckermann, V, Loghdey, R., Ismail, S., Ahmed, F., Engelbrecht, J., Ramdass, A., Maharajh, S., Oosthuysen, W., Angel, G., Bester, C., Booysen, M., Boshoff, C., Cannon, C., Cassimjee, S., Chami, C., Conway, G., Davids, A., de Meyer, L., Du Plessis, G., Ellis, T., Henley, L., Karsten, M., Loyd, E., Marks, J., Mavhusa, L., Mostert, M., Page, A., Rikhotso, L., Salie, M., Sasto, J., Shaik, F., Skein, A., Smith, L., Tarr, G., Tau, T., van Zyl, F., Al Mahmeed, W., Yousef, G., Agrawal, A., Nathani, M., Esheiba, E. M., Singh, R., Naguib, A., Abu-Mahfouz, M., Al Omairi, M., Al Naeemi, A., Maruthanayagam, R., Bazargani, N., Wassef, A., Gupta, R., Khan, M., Subbaraman, B., Abdul, A., Al Mulla, A., El Bardisy, S., Haridas, P., Jadhav, S., Magdaluyo, K., Makdad, M., Maqsood, I, Mohamed, R., Sharma, N., Sharma, R., Thanzeel, M., Goldhaber, S. Z., Canosa, R., Rama, P., Blumberg, E., Garcia, J., Mullen, P., Wilson, V, Quick, A., Ferrick, K., Kutayli, W. M., Cox, M., Franco, M., Falkowski, S., Mendelson, R., Williams, M., Miller, S., Beach, S., Alfieri, A., Gutowski, T., Haque, I, Reddy, R., Ahmed, W., Delafontaine, P., Diercks, D., Theodoro, D., Remmel, K., Alberts, M., Ison, R., Noveck, H., Duffy, P., Pitta, S., Nishijima, D., Treasure, C., Asafu-Adjaye, N., Ball, K., Bartlett, M., Bentley, M., Bowers, S., Brown, A., Browne, A., Cameron-Watts, J., Canova, M., Cassidy, D., Cervellione, K., Congal, S., DePauw, J., Dickerson, A., Eley, M., Evans, L., Accetta, Gabriele, Fitzmaurice, David A., Fox, Keith A. A., Gao, Haiyan, Kayani, Gloria, Pieper, Karen, Kakkar, Ajay K., Ferenczi, J., May, Z., Papp, A., Vertes, A., Juhasz, F., Szentpeteri, I, Kanakaridisz, N., Juhasz, G., Noori, E., Habon, T., Polgar, P., Gaszner, B., Matoltsy, A., Laszlo, Z., Nagy, A., Boda, Z., Kancz, S., Merkely, B., Szalai, G., Vangel, S., Keltai, M., Zincke, S., Ziefle, S., Zauzig, H-D, Zak, J., Wurziger, J., Wolf, T., Wildenauer, S., Wesendorf, S., Weiser, U., Voigts, B., Voelkel-Babyesiza, R., Toennishoff, T., Tetlak, A., Tauber, K., Talkenberger, A., Spranger, K., Sommer, S., Simon, S., Schuppe, M., Schulze, J., Schoene, R., Schmidt, K., Schirmer, K., Scharrer, S., Schaefer, B., Reimer, C., Reichelt, C., Ravenhorst, C., Quietzsch, A., Pomper, L., Plauskat, A., Nicolaus, D., Nasser, N., Mortan, H., Mikes, K., Menken, G., Maselli, A., Mann, L., Lehmann, R., Krueger, A., Kroll, D., Klein, V, Krzesiak-Lodyga, A., Kruczyk, D., Kremis, E., Kowalczyk, H. K., Kowal, E., Korczowska, E., Konopka, A., Komlo, A., Kolodzinska, A., Kociolek, D., Kochanska, E., Kobielusz-Gembala, I, Kluczewski, M., Klata, M., Kiliszek, M., Kaliszczak, R., Kalin, K., Kaczmarzyk-Radka, A., Kabat, J., Jaworska-Drozdowska, M., Jaskulska-Niedziela, E., Jarzebowski, A., Jargiello-Baszak, M., Jaremczuk-Kaczmarczyk, A., Jankielewicz, J., Jaguszewska, G., Jackun-Podlesna, A., Guziewicz, M., Gutknecht, P., Gosciniecka, B., Gasior, E., Gadzinski, W., Frankiewicz, A., Figura-Chmielewska, M., Faron, W., Dziuba, M., Dybala, T., Dudzik-Richter, B., Drelich, L., Dolecka, B., Danilowicz-Szymanowicz, L., Czamara, M., Curyllo, B., Cieszynska, A., Cieslak, K., Cichomski, R., Chojnowski, P., Chmielowski, A., Bzymek, R., Brzustowska, M., Brzozowski, W., Broton, E., Blaszczyk, D., Biernacka, A., Biedrzycki, L., Bernat, L., Bekieszczuk, E., Basiak, M., Bartnik, J., Bartkowiak, R., Barszcz, A., Araminowicz, J., Andrzejewski, D., Ambicka, M., Lesnik, J., Nessler, J., Domanska, E., Raczak, G., Rusicka-Piekarz, T., Baszak, J., Lysek, R., Mazur, S., Myszka, W., Miekus, P., Jurowiecki, J., Cymerman, K., Galbas, K., Wozniak-Skowerska, I, Kukla, P., Okopien, B., Sciborski, R., Jaworska, K., Ruszkowski, P., Glanowska, G., Ogorek, M. (Michal), Bronisz, M., Opolski, G., Trusz-Gluza, M., Chmielnicka-Pruszczynska, M., Karczmarczyk, A., Zinka, E., Lewczuk, J., Ostrowska-Pomian, B., Lajkowski, Z., Krzciuk, M., Kania, G., Olszewski, M., Minc, P., Gruchala, M., Kucharski, L., Swiatkowska-Byczynska, L., Hiczkiewicz, J., Zaluska, R., Kuzniar, J., Supinski, W., Kosior, J., Loboz-Grudzien, K., Wozakowska-Kaplon, B., Ogorek, M. (Marcin), Biedrzycka, M., Gieroba, A., Korzeniak, R., Stepinska, J., Strand, S., Ringdalen, K., O'Donovan, M., Nilsen, V, Lensebraaten, A. B., Jekthammer, A., Dominguez, I, Claussen, H., Ausen, K., Antonsen, H., Otterstad, J. E., Berg-Johansen, J., Henrichsen, S. Hoegh, Oien, T., Christersson, P., Svilaas, A., Ghezai, B., Ostrem, A., Skjelvan, G., Hallaraker, A.
Přispěvatelé:	Bassand, J. -P., Accetta, G., Al Mahmeed, W., Corbalan, R., Eikelboom, J., Fitzmaurice, D. A., Fox, K. A. A., Gao, H., Goldhaber, S. Z., Goto, S., Haas, S., Kayani, G., Pieper, K., Turpie, A. G. G., Van Eickels, M., Verheugt, F. W. A., Kakkar, A. K., Hacke, W., Mantovani, L. G., Gersh, B. J., Luciardi, H. L., Gibbs, H., Brodmann, M., Cools, F., Barretto, A. C. P., Connolly, S. J., Spyropoulos, A., Hu, D., Jansky, P., Nielsen, J. D., Ragy, H., Raatikainen, P., Le Heuzey, J. -Y., Darius, H., Keltai, M., Kakkar, S., Sawhney, J. P. S., Agnelli, G., Ambrosio, G., Koretsune, Y., Diaz, C. J. S., ten Cate, H., Atar, D., Stepinska, J., Panchenko, E., Lim, T. W., Jacobson, B., Oh, S., Vinolas, X., Rosenqvist, M., Steffel, J., Angchaisuksiri, P., Parkhomenko, A., Chen, K. N., Zhao, Y. S., Zhang, H. Q., Chen, J. Z., Cao, S. P., Wang, D. W., Yang, Y. J., Li, W. H., Yin, Y. H., Tao, G. Z., Yang, P., Chen, Y. M., He, S. H., Wang, Y., Fu, G. S., Li, X., Wu, T. G., Cheng, X. S., Yan, X. W., Zhao, R. P., Chen, M. S., Xiong, L. G., Chen, P., Jiao, Y., Guo, Y., Xue, L., Wang, F. Z., Li, H., Yang, Z. M., Bai, C. L., Chen, J., Chen, J. Y., Chen, X., Feng, S., Fu, Q. H., Gao, X. J., Guo, W. N., He, R. H., He, X. A., Hu, X. S., Huang, X. F., Li, B., Li, J., Li, L., Li, Y. H., Liu, T. T., Liu, W. L., Liu, Y. Y., Lu, Z. C., Luo, X. L., Ma, T. Y., Peng, J. Q., Sheng, X., Shi, X. J., Sun, Y. H., Tian, G., Wang, K., Wang, L., Wu, R. N., Xie, Q., Xu, R. Y., Yang, J. S., Yang, L. L., Yang, Q., Ye, Y., Yu, H. Y., Yu, J. H., Yu, T., Zhai, H., Zhan, Q., Zhang, G. S., Zhang, Q., Zhang, R., Zhang, Y., Zheng, W. Y., Zhou, B., Zhou, Z. H., Zhu, X. Y., Jadhav, P., Durgaprasad, R., Ravi Shankar, A. G., Rajput, R. K., Bhargava, K., Sarma, R., Srinivas, A., Roy, D., Nagamalesh, U. M., Chopda, M., Kishore, R., Kulkarni, G., Chandwani, P., Pothiwala, R. A., Padinhare Purayil, M., Shah, S., Chawla, K., Kothiwale, V. A., Raghuraman, B., Vijayaraghavan, G., Vijan, V. M., Bantwal, G., Bisne, V., Khan, A., Gupta, J. B., Kumar, S., Jain, D., Abraham, S., Adak, D., Barai, A., Begum, H., Bhattacharjee, P., Dargude, M., Davies, D., Deshpande, B., Dhakrao, P., Dhyani, V., Duhan, S., Earath, M., Ganatra, A., Giradkar, S., Jain, V., Karthikeyan, R., Kasala, L., Kaur, S., Krishnappa, S., Lawande, A., Lokesh, B., Madarkar, N., Meena, R., More, P., Naik, D., Prashanth, K., Rao, M., Rao, N. M., Sadhu, N., Shah, D., Sharma, M., Shiva, P., Singhal, S., Suresh, S., Vanajakshamma, V., Panse, S. G., Kanamori, S., Yamamoto, K., Kumagai, K., Katsuda, Y., Sadamatsu, K., Toyota, F., Mizuno, Y., Misumi, I., Noguchi, H., Ando, S., Suetsugu, T., Minamoto, M., Oda, H., Shiraishi, K., Adachi, S., Chiba, K., Norita, H., Tsuruta, M., Koyanagi, T., Ando, H., Higashi, T., Okada, K., Azakami, S., Komaki, S., Kumeda, K., Murayama, T., Matsumura, J., Oba, Y., Sonoda, R., Goto, K., Minoda, K., Haraguchi, Y., Suefuji, H., Miyagi, H., Kato, H., Nakamura, T., Nandate, H., Zaitsu, R., Fujiura, Y., Yoshimura, A., Numata, H., Ogawa, J., Tatematsu, H., Kamogawa, Y., Murakami, K., Wakasa, Y., Yamasawa, M., Maekawa, H., Abe, S., Kihara, H., Tsunoda, S., Saito, K., Fudo, T., Obunai, K., Tachibana, H., Oba, I., Kuwahata, T., Higa, S., Gushiken, M., Eto, T., Yoshida, H., Ikeda, D., Ishizawa, M., Nakatsuka, M., Murata, K., Ogurusu, C., Shimoyama, M., Akutsu, M., Takamura, I., Hoshino, F., Yokota, N., Iwao, T., Tsuchida, K., Takeuchi, M., Hatori, Y., Kitami, Y., Nakamura, Y., Oyama, R., Ageta, M., Go, Y., Mishima, K., Unoki, T., Morii, S., Shiga, Y., Sumi, H., Nagatomo, T., Sanno, K., Fujisawa, K., Atsuchi, Y., Nagoshi, T., Seto, T., Tabuchi, T., Kameko, M., Nii, K., Oshiro, K., Takezawa, H., Nagano, S., Miyamoto, N., Iwaki, M., Fujii, M., Okawa, M., Abe, M., Saito, T., Mito, T., Nagao, K., Minami, J., Mita, T., Sakuma, I., Taguchi, T., Marusaki, S., Doi, H., Tanaka, M., Fujito, T., Matsuta, M., Kusumoto, T., Kakinoki, S., Ashida, K., Yoshizawa, N., Agata, J., Arasaki, O., Manita, M., Ikemura, M., Fukuoka, S., Murakami, H., Matsukawa, S., Hata, Y., Taniguchi, T., Ko, T., Kubo, H., Imamaki, M., Akiyama, M., Inagaki, M., Odakura, H., Ueda, T., Katsube, Y., Nakata, A., Watanabe, H., Techigawara, M., Igarashi, M., Taga, K., Kimura, T., Tomimoto, S., Shibuya, M., Nakano, M., Ito, K., Seo, T., Hiramitsu, S., Hosokawa, H., Hoshiai, M., Hibino, M., Miyagawa, K., Horie, H., Sugishita, N., Soma, A., Neya, K., Yoshida, T., Mizuguchi, M., Ishiguro, M., Minagawa, T., Wada, M., Mukawa, H., Okuda, F., Nagasaka, S., Abe, Y., Adachi, T., Akahane, K., Amano, T., Aoki, K., Aoyama, T., Arai, H., Arima, S., Arino, T., Asano, H., Asano, T., Azuma, J., Baba, T., Betsuyaku, T., Chibana, H., Date, H., Doiuchi, J., Emura, Y., Endo, M., Fujii, Y., Fujiki, R., Fujisawa, A., Fujisawa, Y., Fukuda, T., Fukui, T., Furukawa, N., Furukawa, T., Furumoto, W., Goto, T., Hamaoka, M., Hanazono, N., Hasegawa, K., Hatsuno, T., Hayashi, Y., Higuchi, K., Hirasawa, K., Hirayama, H., Hirose, M., Hirota, S., Honda, M., Ido, T., Iiji, O., Ikeda, H., Ikeda, K., Ikeoka, K., Imaizumi, M., Inaba, H., Inoue, T., Iseki, F., Ishihara, A., Ishioka, N., Ito, N., Iwase, T., Kakuda, H., Kamata, J., Kanai, H., Kanda, H., Kaneko, M., Kano, H., Kasai, T., Kato, T., Kato, Y., Kawada, Y., Kawai, K., Kawakami, K., Kawakami, S., Kawamoto, T., Kawano, S., Kim, J., Kira, T., Kitazawa, H., Kitazumi, H., Kito, T., Kobayashi, T., Koeda, T., Kojima, J., Komatsu, H., Komatsu, I., Koshibu, Y., Kotani, T., Kozuka, T., Kumai, Y., Kumazaki, T., Maeda, I., Maeda, K., Maruyama, Y., Matsui, S., Matsushita, K., Matsuura, Y., Mineoi, K., Mitsuhashi, H., Miura, N., Miyaguchi, S., Miyajima, S., Miyamoto, H., Miyashita, A., Miyata, S., Mizuguchi, I., Mizuno, A., Mori, T., Moriai, O., Morishita, K., Murai, O., Nagai, S., Nagata, E., Nagata, H., Nakagomi, A., Nakahara, S., Nakamura, M., Nakamura, R., Nakanishi, N., Nakayama, T., Nakazato, R., Nanke, T., Nariyama, J., Niijima, Y., Niinuma, H., Nishida, Y., Nishihata, Y., Nishino, K., Nishioka, H., Nishizawa, K., Niwa, I., Nomura, K., Nomura, S., Nozoe, M., Ogawa, T., Ohara, N., Okada, M., Okamoto, K., Okita, H., Okuyama, M., Ono, H., Ono, T., Pearce, Y. O., Oriso, S., Ota, A., Otaki, E., Saito, Y., Sakai, H., Sakamoto, N., Sakamoto, Y., Samejima, Y., Sasagawa, Y., Sasaguri, H., Sasaki, A., Sasaki, T., Sato, K., Sawano, M., Seki, S., Sekine, Y., Seta, Y., Sezaki, K., Shibata, N., Shiina, Y., Shimono, H., Shimoyama, Y., Shindo, T., Shinohara, H., Shinohe, R., Shinozuka, T., Shirai, T., Shiraiwa, T., Shozawa, Y., Suga, T., Sugimoto, C., Suzuki, K., Suzuki, S., Suzuki, Y., Tada, M., Taguchi, A., Takagi, T., Takagi, Y., Takahashi, K., Takahashi, S., Takai, H., Takanaka, C., Take, S., Takeda, H., Takei, K., Takenaka, K., Tana, T., Tanabe, G., Taya, K., Teragawa, H., Tohyo, S., Toru, S., Tsuchiya, Y., Tsuji, T., Tsuzaki, K., Uchiyama, H., Ueda, O., Ueyama, Y., Wakaki, N., Wakiyama, T., Washizuka, T., Watanabe, M., Yamada, T., Yamagishi, T., Yamaguchi, H., Yamamoto, T., Yamaura, M., Yamazoe, M., Yasui, K., Yokoyama, Y., Yoshida, K., Ching, C. K., Foo, C. G., Chow, J. H., Chen, D. D., Jaufeerally, F. R., Lee, Y. M., Lim, G., Lim, W. T., Thng, S., Yap, S. Y., Yeo, C., Pak, H. N., Kim, J. -B., Kim, J. H., Jang, S. -W., Kim, D. H., Ryu, D. R., Park, S. W., Kim, D. -K., Choi, D. J., Oh, Y. S., Cho, M. -C., Kim, S. -H., Jeon, H. -K., Shin, D. -G., Park, J. S., Park, H. K., Han, S. -J., Sung, J. H., Cho, J. -G., Nam, G. -B., On, Y. K., Lim, H. E., Kwak, J. J., Cha, T. -J., Hong, T. J., Park, S. H., Yoon, J. H., Kim, N. -H., Kim, K. -S., Jung, B. C., Hwang, G. -S., Kim, C. -J., Kim, D. B., Ahn, J. J., An, H. J., Bae, H., Baek, A. L., Chi, W. J., Choi, E. A., Choi, E. H., Choi, H. K., Choi, H. S., Han, S., Heo, E. S., Her, K. O., Hwang, S. W., Jang, E. M., Jang, H. -S., Jang, S., Jeon, H. -G., Jeon, S. R., Jeon, Y. R., Jeong, H. K., Jung, I. -A., Kim, H. J., Kim, J. S., Kim, J. A., Kim, K. T., Kim, M. S., Kim, S. H., Kim, Y. -I., Lee, C. S., Lee, E. H., Lee, G. H., Lee, H. Y., Lee, H. -Y., Lee, K. H., Lee, K. R., Lee, M. S., Lee, M. -Y., Lee, R. W., Lee, S. E., Lee, S. H., Lee, S., Lee, W. Y., Noh, I. K., Park, A. R., Park, B. R., Park, H. N., Park, J. H., Park, M., Park, Y., Seo, S. -Y., Shim, J., Sim, J. H., Sohn, Y. M., Son, W. S., Son, Y. S., Song, H. J., Wi, H. K., Woo, J. J., Ye, S., Yim, K. H., Yoo, K. M., Yoon, E. J., Yun, S. 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Rok vydání:	2018
Předmět:	Registrie Male Vascular damage Radboud Institute for Health Sciences [Radboudumc 16] lcsh:Medicine Management of atrial fibrillation Comorbidity 030204 cardiovascular system & hematology Pathology and Laboratory Medicine ACE inhibitor therapy Vascular Medicine Biochemistry Cohort Studies 0302 clinical medicine Risk Factors Atrial Fibrillation Chronic Kidney Disease Medicine and Health Sciences 030212 general & internal medicine Prospective Studies Registries Lipid Hormones lcsh:Science Prospective cohort study Diuretics Stroke Aldosterone Aged 80 and over Multidisciplinary Fibrinolytic Agent Pharmaceutics Drugs Atrial fibrillation Cardiovascular therapy Death Treatment Outcome Nephrology Cohort Female Drug therapy Arrhythmia Cohort study Human Research Article medicine.medical_specialty Cardiology Hemorrhage Risk Assessment 03 medical and health sciences Signs and Symptoms Fibrinolytic Agents Diagnostic Medicine Internal medicine Journal Article medicine Humans Vascular Diseases Renal Insufficiency Chronic medicine (all) Aged Heart Failure Pharmacology business.industry Risk Factor lcsh:R Anticoagulant Statins Anticoagulants Biology and Life Sciences medicine.disease Hormones Prospective Studie lcsh:Q Cohort Studie business RC Kidney disease
Zdroj:	PLoS One, 13 PLoS ONE Bassand, J-P, Accetta, G, Al Mahmeed, W, Corbalan, R, Eikelboom, J, Fitzmaurice, D A, Fox, K A A, Gao, H, Goldhaber, S Z, Goto, S, Haas, S, Kayani, G, Pieper, K, Turpie, A G G, van Eickels, M & Verheugt, F W A & Kakkar, A K 2018, ' Risk factors for death, stroke, and bleeding in 28,628 patients from the GARFIELD-AF registry : Rationale for comprehensive management of atrial fibrillation ', PLoS ONE, vol. 13, no. 1, pp. e0191592 . https://doi.org/10.1371/journal.pone.0191592 PLoS ONE, Vol 13, Iss 1, p e0191592 (2018) PLoS One, 13, 1
ISSN:	1932-6203
DOI:	10.1371/journal.pone.0191592
Popis:	Contains fulltext : 190537.pdf (Publisher’s version ) (Open Access) BACKGROUND: The factors influencing three major outcomes-death, stroke/systemic embolism (SE), and major bleeding-have not been investigated in a large international cohort of unselected patients with newly diagnosed atrial fibrillation (AF). METHODS AND RESULTS: In 28,628 patients prospectively enrolled in the GARFIELD-AF registry with 2-year follow-up, we aimed at analysing: (1) the variables influencing outcomes; (2) the extent of implementation of guideline-recommended therapies in comorbidities that strongly affect outcomes. Median (IQR) age was 71.0 (63.0 to 78.0) years, 44.4% of patients were female, median (IQR) CHA2DS2-VASc score was 3.0 (2.0 to 4.0); 63.3% of patients were on anticoagulants (ACs) with or without antiplatelet (AP) therapy, 24.5% AP monotherapy, and 12.2% no antithrombotic therapy. At 2 years, rates (95% CI) of death, stroke/SE, and major bleeding were 3.84 (3.68; 4.02), 1.27 (1.18; 1.38), and 0.71 (0.64; 0.79) per 100 person-years. Age, history of stroke/SE, vascular disease (VascD), and chronic kidney disease (CKD) were associated with the risks of all three outcomes. Congestive heart failure (CHF) was associated with the risks of death and stroke/SE. Smoking, non-paroxysmal forms of AF, and history of bleeding were associated with the risk of death, female sex and heavy drinking with the risk of stroke/SE. Asian race was associated with lower risks of death and major bleeding versus other races. AC treatment was associated with 30% and 28% lower risks of death and stroke/SE, respectively, compared with no AC treatment. Rates of prescription of guideline-recommended drugs were suboptimal in patients with CHF, VascD, or CKD. CONCLUSIONS: Our data show that several variables are associated with the risk of one or more outcomes, in terms of death, stroke/SE, and major bleeding. Comprehensive management of AF should encompass, besides anticoagulation, improved implementation of guideline-recommended therapies for comorbidities strongly associated with outcomes, namely CHF, VascD, and CKD. TRIAL REGISTRATION: ClinicalTrials.gov NCT01090362.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf376f1e8ad3d33a525ea867e1e7225 http://hdl.handle.net/2066/190537 Zobrazit plný text záznamu