Male contraceptive development: A medicinal chemistry perspective

Autor:	Neil R. Norcross, Irene Georgiou, Zoe C. Johnston, Franz S. Gruber, Jason R. Swedlow, Kevin D. Read, Christopher LR. Barratt, Ian H. Gilbert
Rok vydání:	2022
Předmět:	Pharmacology Male Contraceptive Agents Chemistry Pharmaceutical Organic Chemistry Drug Discovery Contraceptive Agents Male Humans General Medicine
Zdroj:	European journal of medicinal chemistry. 243
ISSN:	1768-3254
Popis:	There is a need for non-hormonal contraceptives. One area that needs further investigation is the development of male contraceptives. Comparatively little is understood about potential drug targets in men to achieve a reversible contraceptive effect. In this article, we review the need for male contraceptives and some thoughts around the characteristics of a male contraceptive and the potential development pathway. We then discuss different potential approaches to discovering male contraceptives and then highlight potential targets that have been discussed in the literature.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ced93c8d835649047f8d729d5ad37cb https://pubmed.ncbi.nlm.nih.gov/36087385 Zobrazit plný text záznamu Full Text from ScienceDirect