First characterization of the faecal resistome of eurasian otter (Lutra lutra), a sentinel species for aquatic environments

Autor:	Diana Dias, Carlos Fonseca, Sónia Mendo, Tânia Caetano
Rok vydání:	2021
Předmět:	Environmental Engineering Health Toxicology and Mutagenesis Sentinel Species Public Health Environmental and Occupational Health Escherichia coli Environmental Chemistry Animals Environmental Pollutants General Medicine General Chemistry Pollution Otters Anti-Bacterial Agents
Zdroj:	Chemosphere. 309(Pt 1)
ISSN:	1879-1298
Popis:	Antimicrobial resistance (AMR) is a global health concern. Nowadays, antibiotic resistance genes (ARGs) are considered emerging pollutants. This study followed the One Health framework, in which AMR surveillance in the environment, including in wild animals, is advisable to mitigate this problem. Here we investigated AMR associated with Eurasian otter, a semi-aquatic mammal considered an indicator of freshwater health. To do so, otter's faecal resistome was characterized by a high-throughput qPCR array. This technique has a high-capacity of ARGs profiling. Additionally, we have assessed the antimicrobial susceptibility of two indicator bacteria, E. coli and Enterococcus spp, isolated from otter spraints and interpreted the results according to clinical and epidemiological cut-offs (ECOFFs).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ceb71ac002f87d92cecb572c827db46 https://pubmed.ncbi.nlm.nih.gov/36181859 Zobrazit plný text záznamu Full Text from ScienceDirect