Target motion management in breast cancer radiation therapy
| Autor: | Elham Piruzan, Seied Rabi Mahdavi, Naser Vosoughi, Leila Khalafi, Hojjat Mahani |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Movement medicine.medical_treatment intrafractional movement R895-920 Breast Neoplasms Review target motion Medical physics. Medical radiology. Nuclear medicine breast cancer Breast cancer medicine Humans Radiology Nuclear Medicine and imaging Particle therapy medicine.diagnostic_test business.industry Motion management Cancer Magnetic resonance imaging medicine.disease Radiation therapy particle therapy Oncology Intrafractional motion Female Radiology Dose rate business Radiotherapy Image-Guided |
| Zdroj: | Radiology and Oncology Radiology and Oncology, Vol 55, Iss 4, Pp 393-408 (2021) |
| ISSN: | 1581-3207 |
| DOI: | 10.2478/raon-2021-0040 |
| Popis: | Background Over the last two decades, breast cancer remains the main cause of cancer deaths in women. To treat this type of cancer, radiation therapy (RT) has proved to be efficient. RT for breast cancer is, however, challenged by intrafractional motion caused by respiration. The problem is more severe for the left-sided breast cancer due to the proximity to the heart as an organ-at-risk. While particle therapy results in superior dose characteristics than conventional RT, due to the physics of particle interactions in the body, particle therapy is more sensitive to target motion. Conclusions This review highlights current and emerging strategies for the management of intrafractional target motion in breast cancer treatment with an emphasis on particle therapy, as a modern RT technique. There are major challenges associated with transferring real-time motion monitoring technologies from photon to particles beams. Surface imaging would be the dominant imaging modality for real-time intrafractional motion monitoring for breast cancer. The magnetic resonance imaging (MRI) guidance and ultra high dose rate (FLASH)-RT seem to be state-of-the-art approaches to deal with 4D RT for breast cancer. |
| Databáze: | OpenAIRE |
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