Widespread Bullous Fixed Drug Eruption Mimicking Toxic Epidermal Necrolysis
| Autor: | Richard L. De Villez, Bonnie J. Baird |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Adult
Male Drug medicine.medical_specialty Sulfamethoxazole media_common.quotation_subject Diagnostico diferencial Dermatology Favorable prognosis Trimethoprim Diagnosis Differential Anti-Infective Agents Trimethoprim Sulfamethoxazole Drug Combination medicine Humans media_common LYELL SYNDROME Skin Diseases Vesiculobullous business.industry medicine.disease Toxic epidermal necrolysis Drug eruption Drug Combinations Phenytoin Stevens-Johnson Syndrome Female business |
| Zdroj: | International Journal of Dermatology. 27:170-174 |
| ISSN: | 1365-4632 0011-9059 |
| DOI: | 10.1111/j.1365-4362.1988.tb04923.x |
| Popis: | This paper is written to heighten awareness of the presence of the most severe form of fixed drug eruption. Two patients with a widespread bullous form of fixed drug eruption (FDE) were initially given the diagnosis of toxic epidermal necrolysis (TEN). Both gave a history of a previous widespread eruption from the responsible drug, each had biopsies consistent with fixed drug eruption, and most importantly, both had an uncomplicated course, with complete cutaneous reepithelialization within 10 days. These observations suggest that widespread bullous fixed drug eruption may portend a more favorable prognosis than TEN, thus stressing the potential importance of distinguishing the two diseases. A review of fixed drug eruption and possible means of differentiating the widespread bullous form from TEN are discussed. |
| Databáze: | OpenAIRE |
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