Scintimammography: the complementary role of Tc-99m sestamibi prone breast imaging for the diagnosis of breast carcinoma
| Autor: | S Khalkhali, R. Venegas, S R Klein, J A Cutrone, Iraj Khalkhali, B L Jackson, J F Moss, H. I. Vargas, L. Diggles, I G Mena |
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| Rok vydání: | 1995 |
| Předmět: |
Breast biopsy
Technetium Tc 99m Sestamibi medicine.medical_specialty Breast imaging Breast Neoplasms Scintigraphy Sensitivity and Specificity Predictive Value of Tests medicine Carcinoma Prone Position Mammography Humans Radiology Nuclear Medicine and imaging False Positive Reactions Breast Fibrocystic Breast Disease Radionuclide Imaging False Negative Reactions Scintimammography medicine.diagnostic_test business.industry Biopsy Needle Carcinoma Ductal Breast Middle Aged medicine.disease Fibroadenoma Female Radiology Breast carcinoma Nuclear medicine business Carcinoma in Situ |
| Zdroj: | Radiology. 196(2) |
| ISSN: | 0033-8419 |
| Popis: | To evaluate the complementary role of technetium-99m sestamibi scintimammography in improvement of the sensitivity and specificity of mammography in detection of carcinoma of the breast.At 5 and 60 minutes after intravenous injection of Tc-99m sestamibi, scintimammograms were obtained in 147 women (age range, 18-73 years; mean age, 47.9 years +/- 10.2 [standard deviation]) with 153 lesions that warranted breast biopsy (102 lesions) or fine-needle aspiration cytologic analysis (51 lesions). There were 113 palpable and 40 nonpalpable lesions. Lesion size on mammograms was 0.8 x 0.6 cm to 15.0 x 11.0 cm (mean, 2.82 cm +/- 1.71 x 2.39 cm +/- 1.56).Scintimammographic findings were true-positive in 47 biopsy-confirmed carcinomas, true-negative in 91 benign lesions, false-positive in 11 lesions with benign histopathologic findings (fibrocystic disease [n = 8] or fibroadenoma [n = 3]), and false-negative in four lesions of infiltrating ductal carcinoma. The sensitivity of scintimammography was 92.2%; specificity, 89.2%; positive predictive value, 81.0%; and negative predictive value, 95.8%.The authors conclude that scintimammography is a sensitive test that can improve the detection of breast carcinoma. |
| Databáze: | OpenAIRE |
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