Stimulation maps: visualization of results of quantitative intraoperative testing for deep brain stimulation surgery

Autor: Jean-Jacques Lemaire, Jerome Coste, Simone Hemm, Karin Wårdell, Erik Schkommodau, Ashesh Shah, Fabiola Alonso, Daniela Pison, Dorian Vogel
Přispěvatelé: Institute for Medical and Analytical Technologies, School of Life Sciences (IMAT), University of Applied Sciences and Arts Northwestern Switzerland (HES-SO), Department of Biomedical Engineering (IMT), Linköping University (LIU), Institut Pascal (IP), SIGMA Clermont (SIGMA Clermont)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Service de Neurochirurgie [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand, This research was jointly funded by the Swiss National Science Foundation (CR3212_153370), the Germaine de Staël program of the Swiss Academy of Engineering Sciences, the French Ministry of Health (2011-A00774-37), the Swedish Research Council (2016-03564) and Swedish Foundation for Strategic Research (BD15-0032).Open access funding provided by Linköping University., Service de Neurochirurgie [CHU Clermont-Ferrand], CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand
Jazyk: angličtina
Rok vydání: 2020
Předmět:
medicine.medical_specialty
Deep brain stimulation
Movement disorders
medicine.medical_treatment
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
Biomedical Engineering
Stimulation
[SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery
computer.software_genre
Electric field simulations
Accelerometry
Data visualization
Essential tremor
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Physical medicine and rehabilitation
Voxel
Monitoring
Intraoperative
Tremor
Image Processing
Computer-Assisted
medicine
Humans
Precision Medicine
business.industry
Brain
medicine.disease
University hospital
3. Good health
Computer Science Applications
Visualization
Surgery
Computer-Assisted
Other Medical Engineering
Original Article
[SDV.IB]Life Sciences [q-bio]/Bioengineering
medicine.symptom
Annan medicinteknik
business
Microelectrodes
computer
030217 neurology & neurosurgery
Deep brain stimulation surgery
Zdroj: Medical and Biological Engineering and Computing
Medical and Biological Engineering and Computing, Springer Verlag, 2020, 58 (4), pp.771-784. ⟨10.1007/s11517-020-02130-y⟩
Medical and Biological Engineering and Computing, 2020, 58 (4), pp.771-784. ⟨10.1007/s11517-020-02130-y⟩
Medical & Biological Engineering & Computing
ISSN: 2016-0356
0140-0118
1741-0444
DOI: 10.1007/s11517-020-02130-y⟩
Popis: Deep brain stimulation (DBS) is an established therapy for movement disorders such as essential tremor (ET). Positioning of the DBS lead in the patients brain is crucial for effective treatment. Extensive evaluations of improvement and adverse effects of stimulation at different positions for various current amplitudes are performed intraoperatively. However, to choose the optimal position of the lead, the information has to be "mentally" visualized and analyzed. This paper introduces a new technique called "stimulation maps," which summarizes and visualizes the high amount of relevant data with the aim to assist in identifying the optimal DBS lead position. It combines three methods: outlines of the relevant anatomical structures, quantitative symptom evaluation, and patient-specific electric field simulations. Through this combination, each voxel in the stimulation region is assigned one value of symptom improvement, resulting in the division of stimulation region into areas with different improvement levels. This technique was applied retrospectively to five ET patients in the University Hospital in Clermont-Ferrand, France. Apart from identifying the optimal implant position, the resultant nine maps show that the highest improvement region is frequently in the posterior subthalamic area. The results demonstrate the utility of the stimulation maps in identifying the optimal implant position. Graphical abstract Funding Agencies|Swiss National Science FoundationSwiss National Science Foundation (SNSF) [CR3212_153370]; Germaine de Stael program of the Swiss Academy of Engineering Sciences; French Ministry of Health [2011-A00774-37]; Swedish Research CouncilSwedish Research Council [2016-03564]; Swedish Foundation for Strategic ResearchSwedish Foundation for Strategic Research [BD15-0032]
Databáze: OpenAIRE
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