Associations between pretreatment physical performance tests and treatment complications in patients with non-small cell lung cancer: A systematic review

Autor: M.J.J. Voorn, R.F.W. Franssen, J.M.W.F. Verlinden, Bart C. Bongers, Maryska L.G. Janssen-Heijnen, G. Bootsma, Dirk Karel Maria De Ruysscher
Rok vydání: 2020
Předmět:
Zdroj: Critical reviews in oncology/hematology. 158
ISSN: 1879-0461
Popis: This systematic review evaluated which outcome variables and cut-off values of pretreatment exercise tests are associated with treatment complications in patients with stage I-III non-small cell lung cancer (NSCLC). PRISMA and Cochrane guidelines were followed. A total of 38 studies with adult patients undergoing treatment for stage I-III NSCLC who completed pretreatment exercise tests, and of whom treatment-related complications were recorded were included. A lower oxygen uptake at peak exercise amongst several other variables on the cardiopulmonary exercise test and a lower performance on field tests, such as the incremental shuttle walk test, stair-climb test, and 6-minute walk test, were associated with a higher risk for postoperative complications and/ or postoperative mortality. Cut-off values were reported in a limited number of studies and were inconsistent. Due to the variety in outcomes, further research is needed to evaluate which outcomes and cut-off values of physical exercise tests are most clinically relevant.
Databáze: OpenAIRE