Vitamins in the monkey brain: An immunocytochemical study
| Autor: | Pilar Marcos, Rafael Coveñas, S. Duleu, D. Bodet, Michel Geffard, Arturo Mangas |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Niacinamide Vitamin medicine.medical_specialty Pyridoxal Central nervous system Anterior commissure Ascorbic Acid Biology Supraoptic nucleus Cellular and Molecular Neuroscience chemistry.chemical_compound Internal medicine Neural Pathways medicine Animals Brain Chemistry Neurons Brain Mapping Nicotinamide Brain Pyridoxine Vitamins Ascorbic acid Immunohistochemistry Axons Macaca fascicularis Endocrinology medicine.anatomical_structure Hypothalamus Anterior chemistry Energy Metabolism Paraventricular Hypothalamic Nucleus medicine.drug |
| Zdroj: | Journal of Chemical Neuroanatomy. 38:1-8 |
| ISSN: | 0891-0618 |
| Popis: | Using highly specific antisera directed against vitamins, the distribution of pyridoxal-, pyridoxine-, vitamin C- and nicotinamide-immunoreactive structures in the monkey (Macaca fascicularis) brain was studied. Neither immunoreactive structures containing pyridoxine or nicotinamide, nor immunoreactive fibers containing vitamin C were found in the monkey brain. However, this work reports the first visualization and the morphological characteristics of pyridoxal- and vitamin C-immunoreactive cell bodies in the mammalian central nervous system using an indirect immunoperoxidase technique. A high density of pyridoxal-immunoreactive cell bodies was found in the paraventricular hypothalamic nucleus and in the supraoptic nucleus and a low density of the same was observed in the periventricular hypothalamic region, whereas a moderate density of vitamin C-immunoreactive cell bodies was observed in the somatosensorial cortex (precentral gyrus). Immunoreactive fibers containing pyridoxal were only visualized in the anterior commissure. The restricted distribution of pyridoxal and vitamin C in the monkey brain suggests that both vitamins could be involved in very specific physiological mechanisms. |
| Databáze: | OpenAIRE |
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