Understanding and avoiding late presentation for HIV diagnosis – study protocol of a trial using mixed methods (FindHIV)
| Autor: | Silke Neusser, Eva Wolf, Knud Schewe, Frederik Valbert, Anja Neumann, Christine Kögl, Nikola Hanhoff, Sven Schellberg, Paul Lauscher, Stefan Preis, Jürgen Wasem, Birgit Mück |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Pediatrics medicine.medical_specialty Delayed Diagnosis Health (social science) Adolescent Social Psychology HIV diagnosis Medizin Human immunodeficiency virus (HIV) HIV Infections Disease medicine.disease_cause Late presentation 03 medical and health sciences 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) Risk Factors medicine Humans 030212 general & internal medicine Cd4 cell count Protocol (science) 030505 public health business.industry Advanced stage Public Health Environmental and Occupational Health medicine.disease CD4 Lymphocyte Count 0305 other medical science business |
| Zdroj: | AIDS Care. 33:1642-1646 |
| ISSN: | 1360-0451 0954-0121 |
| Popis: | Many patients infected with HIV are diagnosed at an advanced stage of illness. These late presenters are individuals with a CD4 cell count of less than 350 cells/µL and/or an AIDS defining disease at initial HIV diagnosis. Purpose of FindHIV is to develop and distribute a questionnaire/scoring system aimed at a reduction in late presentation. FindHIV uses a mixed methods approach. In a first step, primary data of patients were collected. Inclusion criteria were: age ≥ 18 years, cognitive ability and language skills to participate in the study, initial HIV diagnosis within the past 6 months, and patient informed consent. Descriptive methods and regression models are used to identify: (1) patient characteristics associated with late presentation and (2) contacts to the healthcare system with indicator diseases that did not lead to HIV testing. Secondly, a questionnaire/scoring system is created by an expert panel. Afterwards the questionnaire/scoring system is to be disseminated. The greatest challenge was in reaching an adequate sample size. Another risk may be a recall bias. Nevertheless, FindHIV is devised as an in-depth study of the phenomenon of late presentation with potential to significantly improve HIV detection. |
| Databáze: | OpenAIRE |
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