Influence of position and stimulation parameters on intracortical inhibition and facilitation in human tongue motor cortex

Autor: Peter Svensson, Mohit Kothari, Lene Baad-Hansen, Jørgen Feldbæk Nielsen
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Kothari, M, Svensson, P, Nielsen, J F & Baad-Hansen, L 2014, ' Influence of position and stimulation parameters on intracortical inhibition and facilitation in human tongue motor cortex ', Brain Research, vol. 1557, pp. 83-89 . https://doi.org/10.1016/j.brainres.2014.02.017
Kothari, M, Svensson, P, Nielsen, J F & Baad-Hansen, L 2014, ' Influence of position and stimulation parameters on intracortical inhibition and facilitation in human tongue motor cortex. ', 8th World Congress for NeuroRehabilitation, Istanbul, Turkey, 08/04/2014-12/04/2014 . < http://wcnr2014.org/home-24.html >
DOI: 10.1016/j.brainres.2014.02.017
Popis: Paired-pulse transcranial magnetic stimulation (ppTMS) can be used to assess short-interval intracortical inhibitory (SICI) and facilitatory (ICF) networks. Many methodological parameters may however influence the outcome. The aim of the study was to examine the influence of body positions (recline and supine), inter-stimulus intervals (ISI) between the test stimulus (TS) and conditioning stimulus (CS) and intensities of the TS and CS on the degree of SICI and ICF. In study 1 and 2, fourteen and seventeen healthy volunteers participated respectively. ppTMS was applied over the "hot-spot" of the tongue motor cortex and motor evoked potentials (MEPs) were recorded from contralateral tongue muscles. In study 1, single pulse and three ppTMS ISIs: 2, 10, 15 ms were applied 8 times each in three blocks (TS: 120%, 140% and 160% of resting motor threshold (rMT); CS: 80% of rMT) in two different body positions (recline and supine) randomly. In study 2, single pulse and four ppTMS ISIs: 2, 2.5, 3, 3.5 ms were applied 8 times each in randomized order in two blocks (CS: 70% and 80% of rMT; TS: 120% of rMT). There was a significant effect of body position (P=0.049), TS intensities (Pusing ppTMS and SICI and ICF.
Databáze: OpenAIRE