Photobiomodulation of Dental Derived Mesenchymal Stem Cells: A Systematic Review

Autor: Sueli Patricia Harumi Miyagi de Cara, Ivana Márcia Alves Diniz, Gabriela Laranjeira Abe, Márcia Martins Marques, Tamara Kerber Tedesco, Roberta Souza D'Almeida-Couto, Ana Clara Fagundes Pedroni, Maria Stella Moreira, Paula Loures Valle Lima
Rok vydání: 2016
Předmět:
Zdroj: Photomedicine and Laser Surgery. 34:500-508
ISSN: 1557-8550
DOI: 10.1089/pho.2015.4038
Popis: This study aimed to conduct a systematic review of the literature published from 2000 to August 2015, to investigate the effect of photobiomodulation (PBM) therapy on dentoalveolar-derived mesenchymal stem cells (ddMSCs), assessing whether a clear conclusion can be reached from the data presented.Systematic reviews provide the best evidence on the effectiveness of a procedure and permit investigation of factors that may influence the performance of a method. To the best of our knowledge, no previous systematic review has evaluated the effects of PBM only on ddMSCs.The search was conducted in PubMed /MEDLINEFrom the initial 3467 potentially relevant articles identified, 6 were excluded because they were duplicates, and 3453 were considered ineligible based on the inclusion criteria. Therefore, eight articles remained, and these were fully analyzed in order to closely check exclusion criteria items. Only one of them was excluded because the cultured cells studied were not characterized as stem cells. Finally, seven articles served as the basis for this systematic review.PBM therapy has no deleterious effects on ddMSCs. Although no other clear conclusion was obtained because of the scarce number of publications, the results of these studies are pointing to an important tendency of PBM therapy to improve ddMSCs' viability and proliferation.
Databáze: OpenAIRE