Antibiotic resistance pattern of Salmonella species isolated from Typhoid patients in Jigawa state, Nigeria
| Autor: | A D Usman, M Yusha’u, U Adamu, S K Abdulhadi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
esbl
Imipenem Veterinary medicine Salmonella salmonella spp medicine.drug_class Antibiotics Biology medicine.disease medicine.disease_cause bacterial infections and mycoses Microbiology Typhoid fever antibiotics QR1-502 Multiple drug resistance Ciprofloxacin resistance Antibiotic resistance medicine Ceftriaxone medicine.drug |
| Zdroj: | Novel Research in Microbiology Journal, Vol 4, Iss 2, Pp 696-703 (2020) |
| ISSN: | 2537-0294 2537-0286 |
| Popis: | This study was designed to determine the antibiotic resistance pattern of Salmonella spp. isolated from clinical samples of symptomatic and asymptomatic typhoid patients, selected from some hospitals in Jigawa State, Nigeria. Four hundred bacterial isolates were recovered from these samples, were identified as; Salmonella typhimurium, S. enteritidis, S. typhi, S. paratyphi A, and S. paratyphi B using microgen biochemical system, according to the standard techniques. The antibiogram of all these Salmonella spp. were carried out using standard oxoid disc of different antibiotics. Double disc diffusion technique was employed to determine the isolates’ capacity to produce β-lactamase. Results showed 5(1.25%), 0(0.0%), 0(0.0%) of the samples collected were positive for extended spectrum β-lactamases (ESBL), AmpC β-lactamase, and Metallo β-lactamases (MBL), respectively. The antibiogram profile of the isolates showed that 100% of these isolates are susceptible to Imipenem, only 3% exhibited resistance to ceftriaxone, whereas 7% demonstrated resistance to ciprofloxacin. To the best of our knowledge, this the first study of this kind in the Jigawa state, especially on these Salmonella spp. The study concluded that β-lactamases with the capacity of conferring multidrug resistance were recorded in Salmonella spp. isolated from patients in several hospitals of Jigawa State, Nigeria. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|