| Autor: |
Domingo Gomez Pardo, Béranger Duthion, Janine Cossy |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
ARKIVOC, Vol 2014, Iss 3, Pp 239-255 (2014) |
| ISSN: |
1551-7012 |
| DOI: |
10.3998/ark.5550190.p008.252 |
| Popis: |
LY503430, an optically active β-fluoroamine, is a potential therapeutic agent for the Parkinson's disease. Different strategies have been studied to synthesize this molecule using a regioselective and stereospecific rearrangement of β-amino alcohols into β-fluoroamines induced by DAST. This reaction allowed the synthesis of LY503430 with an excellent enantiomeric excess. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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