Acute lymphoblastic leukemia in a 10-year-old boy with cystic fibrosis - improvement of pulmonary function during chemotherapy in spite of intermittent Pseudomonas aeruginosa colonisation

Autor:	Hans-Joachim Mentzel, Jochen G. Mainz, Dopfer R, Bernd Gruhn, K. Kentouche, James F. Beck, Christian Dopfer, Becker S
Rok vydání:	2011
Předmět:	Male medicine.medical_specialty Cystic Fibrosis medicine.medical_treatment Comorbidity Malignancy medicine.disease_cause Gastroenterology Cystic fibrosis Pulmonary function testing hemic and lymphatic diseases Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Pneumonia Bacterial Humans Pseudomonas Infections Risk factor Child Chemotherapy Dose-Response Relationship Drug Pseudomonas aeruginosa business.industry Precursor Cell Lymphoblastic Leukemia-Lymphoma medicine.disease Anti-Bacterial Agents Leukemia Pediatrics Perinatology and Child Health Immunology Prednisone Airway business Lung Volume Measurements Immunosuppressive Agents
Zdroj:	Klinische Padiatrie. 223(6)
ISSN:	1439-3824
Popis:	Multiorgan involvement in cystic fibrosis (CF), including chronic airway infection with pathogens like Pseudomonas aeruginosa, is a critical risk factor in patients with malignancy during aggressive immunosuppressive therapy, and was therefore formerly associated with high mortality rates. A 10 year old boy with CF and acute lymphoblastic leukemia (ALL) underwent induction and reinduction treatment without severe infectious complications whereas lung function improved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb31e8e9e41293fd7d971c836ad04f7 https://pubmed.ncbi.nlm.nih.gov/22012603 Zobrazit plný text záznamu