Thin-section multiplanar reformats from multidetector-row CT data: Utility for assessment of regional tumor extent in non-small cell lung cancer
| Autor: | Hirokazu Watanabe, Chiho Ohbayashi, Kazuro Sugimura, Yoshiharu Ohno, Munenobu Nogami, Miyako Satouchi, Daisuke Takenaka, Masahiko Fujii, Yoshihiro Nishimura, Masahiro Yoshimura, Takanori Higashino |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty Lung Neoplasms Contrast Media Iopanoic Acid Sensitivity and Specificity McNemar's test Carcinoma Non-Small-Cell Lung medicine Humans Radiology Nuclear Medicine and imaging Lung cancer Surgical treatment Lung Aged Aged 80 and over Observer Variation Receiver operating characteristic business.industry Reproducibility of Results Microtomy General Medicine Middle Aged medicine.disease Sagittal plane Iopamidol Radiographic Image Enhancement Data set medicine.anatomical_structure ROC Curve Coronal plane Female Radiology Non small cell Tomography X-Ray Computed business Nuclear medicine |
| Zdroj: | European Journal of Radiology. 56:48-55 |
| ISSN: | 0720-048X |
| DOI: | 10.1016/j.ejrad.2005.04.002 |
| Popis: | To determine the clinical utility of thin-section multiplanar reformats (MPRs) from multidetector-row CT (MDCT) data sets for assessing the extent of regional tumors in non-small cell lung cancer (NSCLC) patients.Sixty consecutive NSCLC patients, who were considered candidates for surgical treatment, underwent contrast-enhanced MDCT examinations, surgical resection and pathological examinations. All MDCT examinations were performed with a 4-detector row computed tomography (CT). From each raw CT data set, 5mm section thickness CT images (routine CT), 1.25 mm section thickness CT images (thin-section CT) and 1.25 mm section thickness sagittal (thin-section sagittal MPR) and coronal images (thin-section coronal MPR) were reconstructed. A 4-point visual score was used to assess mediastinal, interlobar and chest wall invasions on each image set. For assessment of utility in routine clinical practice, mean reading times for each image set were compared by means of Fisher's protected least significant difference (PLSD) test. A receiver operator characteristic (ROC) analysis was performed to determine the diagnostic capability of each of the image data sets. Finally, sensitivity, specificity and accuracy of the reconstructed images were compared by McNemar test.Mean reading times for thin-section sagittal and coronal MPRs were significantly shorter than those for routine CT and thin-section CT (p0.05). Areas under the curve (Azs) showing interlobar invasion on thin-section sagittal and coronal MPRs were significantly larger than that on routine CT (p=0.03), and the Az on thin-section sagittal MPR was also significantly larger than that on routine CT (p=0.02). Accuracy of chest wall invasion by thin-section sagittal MPR was significantly higher than that by routine CT (p=0.04).Thin-section multiplanar reformats from multidetector-row CT data sets are useful for assessing the extent of regional tumors in non-small cell lung cancer patients. |
| Databáze: | OpenAIRE |
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