Enteric multiplex PCR panels: A new diagnostic tool for amoebic liver abscess?
| Autor: | G. Schiappacasse, Valeska Vollrath, Thomas Weitzel, Luis Miguel Noriega, Reinaldo Rosas, Lorena Porte, J. Cabrera |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty diagnosis 030231 tropical medicine 030106 microbiology amoebic liver abscess Biology Microbiology Serology lcsh:Infectious and parasitic diseases New Technologies for Infectious and Tropical Diseases 03 medical and health sciences Entamoeba histolytica 0302 clinical medicine Multiplex polymerase chain reaction medicine In patient lcsh:RC109-216 Amoebiasis Reference standards Amoebic liver abscess medicine.disease biology.organism_classification Infectious Diseases multiplex molecular panel |
| Zdroj: | New Microbes and New Infections New Microbes and New Infections, Vol 18, Iss C, Pp 50-53 (2017) |
| ISSN: | 2052-2975 |
| Popis: | Invasive amoebiasis is a life-threatening infection requiring immediate detection and treatment. However, diagnosis is challenging because conventional methods such as light microscopy and serology are unreliable. Molecular techniques are therefore considered the new diagnostic reference standard, but most of the developed assays are research tools and not widely available. Recently commercial multiplex PCR panels have been introduced which permit the simultaneous detection of multiple enteric pathogens including Entamoeba histolytica in stool samples. Our report demonstrates for the first time that these new assays might also serve as a rapid tool to diagnose amoebic liver abscess in patients with cystic focal liver lesions. |
| Databáze: | OpenAIRE |
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