Clinical and pathologic findings of aphakic peripheral corneal edema: Brown-McLean syndrome
| Autor: | John W. Reed, L Ray Cain, Richard G. Weaver, Sheldon M. Oberfeld |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Male medicine.medical_specialty genetic structures Endothelium Cell Count Aphakia Postcataract Cataract Extraction Corneal edema Ophthalmology medicine Brown-McLean Syndrome Humans Surgical treatment Pigment Epithelium of Eye Intracapsular cataract extraction Aged Aged 80 and over business.industry Corneal Edema Endothelium Corneal Syndrome Middle Aged eye diseases Peripheral medicine.anatomical_structure Female sense organs business Keratoplasty Penetrating |
| Zdroj: | Cornea. 11(6) |
| ISSN: | 0277-3740 |
| Popis: | Twenty-two patients (36 eyes) are reported with Brown- McLean syndrome, which consists of peripheral corneal edema associated with peripheral endothelial pigment deposits, usually after intracapsular cataract extraction. This group, the largest reported to date, had a spectrum of corneal alterations, those at the more severe end of the spectrum being both progressive and symptomatic. Some patients required medical and surgical treatment, including keratoplasty. Four corneas (two obtained surgically, two postmortem) were examined by light and electron microscopy (EM). Centrally, the corneas were relatively normal, but peripherally there were disintegrated endothelial cells with an abnormal posterior collagenous layer of Descemet's membrane. Scanning EM showed a somewhat distinct junction between the normal central endothelium and the diseased peripheral endothelium. |
| Databáze: | OpenAIRE |
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