State of the Science: Stress, Inflammation, and Cancer
| Autor: | Judith K. Payne |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Complementary Therapies
Hypothalamo-Hypophyseal System Coping (psychology) Sympathetic Nervous System Neuroimmunomodulation Pituitary-Adrenal System Inflammation Health outcomes Fight-or-flight response Behavioral risk Disease susceptibility Stress Physiological Neoplasms Humans Medicine State of the science Mind-Body Therapies business.industry Cell Transformation Neoplastic Gene Expression Regulation Chronic Disease Immunology Interdisciplinary Communication Disease Susceptibility medicine.symptom business Stress Psychological Forecasting Genes Neoplasm Clinical psychology |
| Zdroj: | Oncology Nursing Forum. 41:533-540 |
| ISSN: | 1538-0688 0190-535X |
| DOI: | 10.1188/14.onf.533-540 |
| Popis: | Diagnosis with a life-threatening illness such as cancer is almost universally experienced as stressful. The construct of stress has received substantial consideration as a correlate or predictor of psychological and health outcomes (Andersen et al., 2004) and has often been conceptualized within a stress and coping framework (Lazarus & Folkman, 1984). Biobehavioral factors have long been thought to affect many health processes. The relationship between inflammation of stress and cancer originated centuries ago and is now recognized as a facilitating characteristic of cancer (Mantovani, Allavena, Sica, & Balkwill, 2008). In addition, stress and the stress response are probable mediators of the effects of psychological factors on cancer, and specifically on progression of cancer (Powell, Tarr, & Sheridan, 2013). A substantial amount of new research activity has enlightened scientists and clinicians on the neuroendocrine regulatory function of physiologic pathways in cancer growth and progression (Lutgendorf & Sood, 2011). However, in spite of considerable research over the past several decades, inconsistent data remain a challenge in establishing evidence-based pathways between behavioral risk factors and cancer initiation. |
| Databáze: | OpenAIRE |
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