Sialadenitis in patients with chronic hepatitis C is not directly related to hepatitis C virus

Autor:	Mamoru Watanabe, Yuzo Takahashi, Michinori Kohara, Kozo Ishidate, Chifumi Sato, Yujiro Tanaka, Yutaka Amako, Shinya Ohoka
Rok vydání:	2003
Předmět:	Hepatology Salivary gland Hepatitis C virus virus diseases Biology medicine.disease_cause medicine.disease Sialadenitis digestive system diseases Virus Pathogenesis Molecular mimicry Infectious Diseases medicine.anatomical_structure Immunology medicine biology.protein Immunohistochemistry Antibody
Zdroj:	Hepatology Research. 27:23-29
ISSN:	1386-6346
DOI:	10.1016/s1386-6346(03)00196-7
Popis:	Sjogren's syndrome has been suspected to be an extrahepatic manifestation of chronic hepatitis C virus (HCV) infection. To evaluate the association of sialadenitis with HCV infection, serum levels of salivary amylase (s-isoamylase) and antibodies to Ro (SS-A) and La (SS-B) were analyzed in 114 patients with chronic hepatitis C. Serum s-isoamylase levels were monitored before and after HCV was eradicated by interferon therapy. Immunohistochemistry and Western blotting using anti-HCV antibodies, and in situ hybridization of HCV-RNA were performed in the salivary gland. Serum s-isoamylase levels were elevated in patients with chronic hepatitis C (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca161877107e4b2f767b1261a3e69a3 https://doi.org/10.1016/s1386-6346(03)00196-7 Zobrazit plný text záznamu