Heart rate variability: its association with hemodynamic function of the left ventricle in patients with coronary heart disease
| Autor: | Krzysztof Szydło, Artur Filipecki, Leszek Giec, Witold Orszulak, Maria Trusz-Gluza, Janusz Drzewiecki |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
medicine.medical_specialty Cardiac Catheterization Systole Cardiac Volume Cardiac Output Low Hemodynamics Coronary Disease Autonomic Nervous System Coronary Angiography Ventricular Function Left Ventricular Dysfunction Left Diastole Heart Rate Internal medicine medicine Ventricular Pressure Heart rate variability Humans cardiovascular diseases Circadian rhythm Aged Analysis of Variance Ejection fraction business.industry Gated Blood-Pool Imaging Stroke Volume General Medicine Middle Aged medicine.disease Myocardial Contraction Coronary heart disease Circadian Rhythm Autonomic nervous system medicine.anatomical_structure Ventricle Heart failure Cardiology Electrocardiography Ambulatory Linear Models Cardiology and Cardiovascular Medicine business circulatory and respiratory physiology |
| Zdroj: | Pacing and clinical electrophysiology : PACE. 19(11 Pt 2) |
| ISSN: | 0147-8389 |
| Popis: | Patients with heart failure secondary to coronary heart disease (CHD) are characterized by an imbalance of the autonomic nervous system, which can be assessed by analysis of the heart rate variability (HRV). However it is still unclear whether all patients with CHD reveal suppression of HRV and if it is related to hemodynamic function and contractile disturbances of the left ventricle. To answer these questions data from 105 consecutive patients were analyzed and compared with 17 healthy subjects. All study participants underwent 24-hour ambulatory ECG recordings with calculation of HRV parameters and angiographic examination after collection of clinical data and other noninvasive evaluations. Time- (SDRR, SDANN, SD, pNN50) and frequency- (LF, HF) domain parameters of HRV were assessed. All ventriculographic and hemodynamic measurements were used in the analysis. Highly significant correlations were found between all HRV parameters, and left ventricular ejection fraction (LVEF) and left ventricular end-diastolic pressure (P < 0.001). Patients with LVEF < 40% were characterized by significantly lower values of HRV and impairment or lack (LVEF < 20%) of diurnal variation of frequency-domain measurements of HRV. Patients with segmental akinesis or dyskinesis also had lower values of HRV. The group with dyskinesis was characterized by significantly lower diurnal rhythms of LF and HF, independent of LVEF. |
| Databáze: | OpenAIRE |
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